Short Description

More than 40 phenotypes of AAT exist. The inherited deficiency seen most often as the ZZ, SS & SZ phenotypes is associated with Neonatal hepatitis & Infantile cirrhosis. In adults these phenotypes are associated with chronic lung disease including Emphysema & Chronic bronchitis.

PreTest Information

Duly filled Test Send Out Consent Form (Form 35) is mandatory.

Detail Description

ALPHA-1-ANTITRYPSIN (AAT) PHENOTYPE Test: Cost, Symptoms, and Diagnosis

Alpha-1-Antitrypsin (AAT) is a protein produced in the liver that helps protect the lungs from damage caused by inflammation. A deficiency in AAT can lead to lung diseases such as emphysema and chronic obstructive pulmonary disease (COPD). The AAT phenotype test is a blood test that determines a person's AAT protein levels and helps diagnose AAT deficiency.

Symptoms of AAT Deficiency

AAT deficiency is a genetic condition that affects people of all ages and ethnicities. The symptoms of AAT deficiency vary depending on the severity of the deficiency and can include:

• Shortness of breath
• Wheezing
• Chest tightness
• Frequent respiratory infections
• Coughing up blood

These symptoms may be mistaken for other respiratory conditions such as asthma, allergies, or bronchitis.

Diagnosis of AAT Deficiency

The AAT phenotype test is the primary diagnostic tool for AAT deficiency. The test measures the level and type of AAT protein in the blood. The test is usually ordered for people who have symptoms of lung disease or have a family history of AAT deficiency. The results of the test can help determine the severity of the deficiency and guide treatment options.

Cost of AAT Phenotype Test

The cost of the AAT phenotype test in India can vary depending on the laboratory and location. On average, the cost of the test is around INR 18,000.

Conclusion

AAT deficiency is a genetic condition that can lead to lung diseases such as emphysema and COPD. The AAT phenotype test is a blood test that helps diagnose AAT deficiency by measuring the level and type of AAT protein in the blood. If you have symptoms of AAT deficiency or have a family history of the condition, talk to your healthcare provider about getting tested.

At DNA Labs India, we offer reliable and accurate AAT phenotype testing services. Contact us today to schedule your test or to learn more about our genetic testing services.