List of Liquid Biopsy Tests

Liquid Biopsy:

Blood contains two types of cancer-derived materials that are susceptible to detailed molecular analysis: intact circulating tumour cells (CTCs) and cell-free circulating tumour DNA (cfDNA; also referred to as circulating tumour DNA, or ctDNA).

Usually performed on blood, liquid biopsies analyze DNA from whole circulating tumour cells (CTCs) or cell-free DNA (cfDNA) from tumours. Many tests specifically target a type of cfDNA called circulating tumour DNA (ctDNA), most of which comes from cells in the bed of the tumours.

Advantages:

  • A non-invasive method for identification of tumour markers, either as an alternative for patients whose tissue is unable to be biopsied or as an adjunct to evaluate drug response.
  • Possibly less costly than tumour biopsy and analysis.
  • Provides an accurate snapshot of the genomic landscape of the tumour, bypassing issues such as intratumor heterogeneity, as it is speculated that CTCs and cfDNA carry the driver mutations causing metastases.
  • Able to obtain serial samples during treatment to assess for drug resistance and tumour progression. This is not picked up with a tumour biopsy given that tumour biopsies are generally only done prior to treatment, therefore mutations indicating resistance would not be picked up as these generally arise after starting therapy.
  • Unlike tissue biopsy where the tumour DNA is preserved in formalin-fixed paraffin-embedded (FFPE) blocks, DNA cross-linking does not occur with liquid biopsy; thereby facilitating tumour DNA sequencing.

 

Show Filters

Showing all 2 results

Show Filters

Showing all 2 results

List of Liquid Biopsy Test collection centres in India is Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Visakhapatnam, Kanpur, Nagpur, Lucknow, Thane, Bhopal, Indore, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivli, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi, Mumbai, Allahabad, Howrah, Ranchi, Gwalior, Jabalpur, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Chandigarh, Guntur, Guwahati, Solapur, Hubli–Dharwad, Mysore, Tiruchirappalli, Bareilly, Moradabad, Tiruppur, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal, Jalgaon, Kota, Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore, Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola.