MODY NGS panel Test Details:
MODY panel (NGS Panel ABCC8, BLK, CEL, GCK, HNF1A, HNF1B, HNF4A, INS, KCNJ11, KLF11, NEUROD1, NKX2-2, PAX4, PDX1, RFX6, ZFP57)
What is MODY:
Maturity-Onset Diabetes of the Young (MODY), which is an intermediate transition type of diabetes disease spectrum, is a chronic hyperglycemia syndrome characterized by defects in insulin secretion.
Insulin deficiency is between type-1 and type-2 diabetes. The clinical manifestations of MODY have some characteristics of both, so it is classified as special type diabetes.
MODY is diabetes caused by a single gene mutation, which leads to genetic defects in islet β-cell function. It has an early onset and autosomal dominant inheritance.
MODY contains at least 6 subtypes, each of which has different clinical phenotypes, mainly characterized by hyperglycemia, polyuria and polydipsia, microvascular complications, macrovascular complications and other common symptoms of diabetes.
Clinical Features of MODY:
Clinical features of MODY depend on the gene mutations a person has. People with certain types of mutations may have slightly high blood sugar levels that remain stable throughout life, have mild or no symptoms of diabetes, and do not develop any long-term complications.
Their high blood glucose levels may only be discovered during routine blood tests. However, other mutations require specific treatment with either insulin or a type of oral diabetes medication called sulfonylureas.
Types of MODY:
The most common types of MODY are:
HNF1-alpha: This gene causes about 70 per cent of cases of MODY. It causes diabetes by lowering the amount of insulin made by the pancreas. Diabetes usually develops in adolescence or early twenties.
HNF4-alpha: This isn’t as common as the other forms of MODY. People who have inherited a change in this gene are likely to have had a birth weight of 9lb or more (around 4kg).
HNF1-beta: People with this type of MODY can have a variety of problems including renal cysts (cysts of the kidneys), uterine abnormalities and gout, as well as diabetes. Often the renal cysts can be detected in the womb before a baby is born.
Glucokinase: This gene helps the body to recognise how high the blood glucose level is in the body. When this gene isn’t working properly the body allows the level of blood glucose to be higher than it should be.
Why is it important to recognize MODY?
- There are different types of MODY. By finding out which type of MODY a person has the most appropriate treatment for them can be determined.
- Knowing the type of MODY a person has also meant we can advise them about how their diabetes will progress in the future.
- As it runs in families, it is important to advise other family members of their risk of inheriting it.
What is MODY NGS panel Test?
MODY NGS panel Test is a medical speciality that determines the cause and nature of diseases by examining and testing body tissues (EDTA blood or DNA). It is a MODY NGS panel Test that screens for serious conditions.
What type of sample are needed to do a MODY NGS panel Test?
An EDTA blood or DNA for testing can be obtained from several bodily sources. The cells are the most commonly tested are derived.
Standard Biological MODY NGS panel Test Samples: EDTA blood or DNA
How accurate is MODY NGS panel Test?
MODY NGS panel Test is generally considered to be the most accurate testing method available. DNA Labs India’s MODY NGS panel Test is considered as a benchmark by most doctors. The most precise and accurate MODY NGS panel Test in India.
How many days does it take to obtain MODY NGS panel Test results?
Results of MODY NGS panel Test test are usually available from the laboratory within 1 week to 5 weeks.
For a standard MODY NGS panel Test, DNA Labs India returns MODY NGS panel Test results in 7 to 10 business days once all samples are received at the lab.
DNA Labs India understands that waiting for MODY NGS panel Test results for this potentially life-changing test is stressful, so we provide speedy service without sacrificing accuracy.
Once complete, results are posted immediately to our secure online portal, and you will be notified by email right away.
Can the MODY NGS panel Test be done during pregnancy?
Prenatal MODY NGS panel Test is a sensitive subject because of the ethical and legal issues involved, including the risks of an invasive test. You need to talk with your doctor.
How much does a MODY NGS panel Test cost?
A standard MODY NGS panel Test cost you 20000/- INR.
Why Choose DNA Labs India for MODY NGS panel Test?
DNA labs India’s MODY NGS panel Test follows with dual testing for 100% accuracy when determining a MODY NGS panel Test.
- We are the leading lab for MODY NGS panel Test in India
- Greater Accuracy
- Collection centres across India
- Outstanding customer service
- Strict privacy and confidentiality assured
- Full-service laboratories providing testing for use in complex cases
How to Schedule an Appointment for MODY NGS panel Test?
You can either book online at the link provided. If you book and make the payment online free home collection service is provided to patients of all MODY NGS panel Test.
How can I locate a MODY NGS panel Test facility?
DNA labs India has 3000 plus sample collection centres across India for MODY NGS panel Test.
You can choose the centre and book the MODY NGS panel Test online. For all online bookings made and payment paid a free home sample collection service is provided.
List of MODY NGS panel Test collection centres in India is Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Visakhapatnam, Kanpur, Nagpur, Lucknow, Thane, Bhopal, Indore, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivli, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi, Mumbai, Allahabad, Howrah, Ranchi, Gwalior, Jabalpur, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Chandigarh, Guntur, Guwahati, Solapur, Hubli–Dharwad, Mysore, Tiruchirappalli, Bareilly, Moradabad, Tiruppur, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal, Jalgaon, Kota, Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore, Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola.