Overview
Eukaryotic mRNA sequencing and de novo analysis is a cutting-edge genetic test that sequences messenger RNA (mRNA) from eukaryotic organisms, such as humans, animals, and plants. Unlike traditional DNA sequencing, this test focuses on the transcriptome—the complete set of RNA transcripts produced by the genome. The 'de novo' aspect means that the transcriptome is assembled without a reference genome, making it ideal for organisms with incomplete genomic data. This approach allows for the identification of novel genes, alternative splicing events, and quantitative gene expression levels. At DNA Labs India, this test is offered at a cost of INR 35,000, which includes sequencing, de novo assembly, and comprehensive bioinformatics analysis. The test is particularly valuable in diagnosing rare genetic disorders, identifying cancer-causing mutations, and guiding personalized treatment strategies. By analyzing mRNA, clinicians can gain insights into functional genetic changes that may not be apparent from DNA sequencing alone. This test is performed on extracted DNA samples, with a turnaround time of 8 weeks. DNA Labs India provides free home sample collection across major cities in India, ensuring accessibility and convenience for patients.
To be completed — reclassified from Tests on 2026-11-13.
The primary purpose of eukaryotic mRNA sequencing and de novo analysis is to provide a comprehensive view of gene expression and identify genetic abnormalities that may be responsible for various diseases. This test is used to: 1) Detect novel or known mutations in genes associated with rare genetic disorders. 2) Identify alternative splicing events that may lead to dysfunctional proteins. 3) Quantify gene expression levels to understand disease mechanisms. 4) Discover novel transcripts and non-coding RNAs that may play a role in disease. 5) Aid in cancer diagnosis by identifying mutations in oncogenes and tumor suppressor genes. 6) Guide targeted therapy selection based on the specific genetic profile of a tumor. 7) Support research in fields such as developmental biology and pharmacogenomics.
Sample requirements
What to send us
Deliverables & turnaround
What you receive
Turnaround: Results are typically available within 8 weeks after the sample reaches the laboratory.
Pricing
Transparent pricing
| Option | Turnaround | Price (INR) | Unit |
|---|---|---|---|
| Standard | Results are typically available within 8... | ₹35,000 | per sample |
Limitations & precautions
What this service cannot do
Questions customers ask
Frequently asked questions
What is eukaryotic mRNA sequencing and de novo analysis?
It is a test that sequences messenger RNA from eukaryotic cells and assembles the transcriptome without a reference genome, allowing identification of novel genes, splice variants, and expression levels.
How much does the test cost at DNA Labs India?
The test costs INR 35,000, which includes sequencing, de novo assembly, and bioinformatics analysis.
What sample is required for this test?
Extracted DNA is required, typically obtained from a blood sample or tissue biopsy.
Do I need to fast before the test?
No, fasting is not required for this test.
How long does it take to get results?
Results are usually available within 8 weeks after the sample is received.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for online bookings across many cities in India.
What conditions can this test help diagnose?
It can help diagnose rare genetic disorders, cancer, and other conditions where gene expression or splicing abnormalities are suspected.
Is this test covered by insurance?
Insurance coverage varies; it is recommended to check with your insurance provider.
Are there any risks associated with the test?
The test is safe with minimal risks such as slight bleeding or bruising at the blood draw site.
Can this test be used for research purposes?
Yes, it is also used in research to study transcriptomes of various organisms.
What is the difference between mRNA sequencing and DNA sequencing?
mRNA sequencing analyzes gene expression and splicing, while DNA sequencing looks at the genetic code itself.
How should I prepare for the test?
No special preparation is needed, but inform your doctor about any medications you are taking.
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