Overview
Hi-C sequencing is an advanced genomic technique that captures the three-dimensional (3D) organization of chromatin within the nucleus. By cross-linking DNA, fragmenting, and ligating interacting regions, Hi-C generates data that reveals how chromosomes fold and how genes physically interact. This analysis is crucial for identifying structural variations such as translocations, inversions, deletions, and duplications that can disrupt gene regulation and cause disease. At DNA Labs India, our Hi-C sequencing data analysis service provides comprehensive bioinformatics processing, including quality control, alignment, contact matrix generation, and identification of significant chromatin interactions. The service is priced at INR 50000 and includes sequencing, data analysis, and a detailed interpretation report. This test is particularly valuable for patients with unexplained developmental delays, congenital anomalies, or suspected chromosomal rearrangements that are not detected by standard karyotyping or chromosomal microarray. Our expert team ensures accurate and clinically relevant results, aiding in diagnosis and management of genetic disorders.
To be completed — reclassified from Tests on 2026-11-13.
The purpose of Hi-C sequencing data analysis is to map the 3D architecture of the genome and detect structural variants that may underlie genetic disorders. It helps in identifying chromosomal rearrangements, gene fusions, and other aberrations that affect gene expression and disease pathogenesis.
Sample requirements
What to send us
Deliverables & turnaround
What you receive
Turnaround: Reports are typically available within 4 weeks after the sample reaches the laboratory.
Pricing
Transparent pricing
| Option | Turnaround | Price (INR) | Unit |
|---|---|---|---|
| Standard | Reports are typically available within 4... | ₹50,000 | per sample |
Limitations & precautions
What this service cannot do
Questions customers ask
Frequently asked questions
What is Hi-C sequencing data analysis?
Hi-C sequencing data analysis is a bioinformatics process that interprets data from Hi-C experiments to map the 3D structure of the genome. It identifies chromatin interactions and structural variants that may be linked to genetic disorders.
How much does Hi-C sequencing data analysis cost at DNA Labs India?
The cost is INR 50000, which includes sequencing, data analysis, and interpretation. We also offer free home sample collection for online bookings.
What sample is required for Hi-C sequencing data analysis?
The test requires extracted DNA of high quality. Typically, a blood sample is collected for DNA extraction, but tissue samples may also be used.
How long does it take to get results?
Reports are usually available within 4 weeks after the sample is received at the laboratory.
What conditions can Hi-C sequencing data analysis diagnose?
It can help diagnose genetic disorders caused by structural variants such as translocations, inversions, deletions, and duplications. It is also used in oncology to detect gene fusions.
Is fasting required before the test?
No, fasting is not required for Hi-C sequencing data analysis.
Can Hi-C sequencing detect all types of genetic mutations?
No, Hi-C is primarily for structural variants and chromatin organization. It does not detect point mutations or small indels; other tests like whole genome sequencing are needed for those.
Is home sample collection available?
Yes, we offer free home sample collection for online bookings across major cities in India.
Who should consider this test?
Individuals with unexplained developmental delays, intellectual disability, birth defects, seizures, or autism spectrum disorder, especially when standard genetic tests have been inconclusive.
What is the turnaround time for reports?
The turnaround time is approximately 4 weeks from sample receipt.
Are there any risks associated with the test?
The test is safe. The only risk is minimal bruising or infection at the blood draw site, which is rare.
How should I prepare for the test?
No special preparation is needed. However, inform your healthcare provider about any medications you are taking, as they may affect the results.
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