Overview
RNA viral metagenome sequencing and analysis is an advanced molecular diagnostic technique that sequences the entire RNA content of a clinical sample to detect and identify all viral pathogens present, including novel or unexpected viruses. Unlike targeted PCR tests that look for specific viruses, metagenomic sequencing provides a comprehensive, unbiased view of the viral community in a patient's sample. This is particularly valuable in cases where the cause of a viral infection is unknown, when conventional tests are negative, or when a new or emerging virus is suspected. The test involves extracting RNA from the sample, converting it to cDNA, preparing a sequencing library, and performing high-throughput sequencing. The resulting data are analyzed using sophisticated bioinformatics pipelines to identify viral sequences and assemble viral genomes. This approach can also reveal the genetic diversity of viral populations, which is useful for epidemiological tracking and understanding viral evolution. DNA Labs India offers this service at an affordable cost of INR 42000, making advanced viral diagnostics accessible to patients across India. The test is performed in our NABL-accredited laboratory using state-of-the-art sequencing platforms and is interpreted by experienced clinical geneticists and infectious disease specialists. Early and accurate identification of viral pathogens can guide appropriate antiviral therapy, prevent unnecessary antibiotic use, and help control outbreaks. If you or your healthcare provider suspect a viral infection that has not been diagnosed by routine tests, RNA viral metagenome sequencing may be the next step.
To be completed — reclassified from Tests on 2026-11-13.
The purpose of RNA viral metagenome sequencing is to detect and identify all RNA viruses present in a clinical sample, including known, rare, and novel viruses. It is used when a viral infection is strongly suspected but routine tests (e.g., PCR, antigen tests) have been negative or inconclusive. It also helps in characterizing the viral genome, which can inform treatment decisions, infection control measures, and public health responses.
Sample requirements
What to send us
Deliverables & turnaround
What you receive
Turnaround: Results are typically available within 8 weeks due to the complex sequencing and analysis process.
Pricing
Transparent pricing
| Option | Turnaround | Price (INR) | Unit |
|---|---|---|---|
| Standard | Results are typically available within 8... | ₹42,000 | per sample |
Limitations & precautions
What this service cannot do
Questions customers ask
Frequently asked questions
What is RNA viral metagenome sequencing?
It is an advanced technique that sequences all RNA in a sample to detect and identify any viral RNA present, including novel or unexpected viruses.
How is this test different from a PCR test?
PCR looks for specific known viruses, while metagenomic sequencing is unbiased and can detect any virus, including new ones, without prior knowledge.
What sample types are accepted?
Common samples include blood, cerebrospinal fluid (CSF), respiratory swabs, and tissue biopsies. The appropriate sample depends on the suspected infection.
Do I need to fast for this test?
No, fasting is not required for this test.
How long does it take to get results?
Results are typically available within 8 weeks due to the complex sequencing and bioinformatics analysis.
Is home sample collection available?
Yes, DNA Labs India offers free home sample collection for this test in many cities across India.
What is the cost of the test?
The test costs Rs 42000, which includes sample collection, sequencing, and analysis.
Can this test detect all viruses?
It can detect RNA viruses. DNA viruses are not detected by this test, as it specifically sequences RNA.
Is this test covered by insurance?
Currently, this test is not covered by most insurance schemes. Please check with your provider for coverage details.
Who should consider this test?
Patients with unexplained viral symptoms, negative routine tests, or suspected novel viral infections may benefit from this test.
Are there any risks associated with the test?
Risks are minimal and related to sample collection, such as bruising from blood draw or headache after lumbar puncture.
How should I prepare for the test?
No special preparation is needed. Inform your doctor about any medications you are taking.
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