DNA Labs India: ABCB11 Gene Cholestasis Progressive Intrahepatic Type 2 NGS Genetic Test

Cholestasis Progressive Intrahepatic Type 2 (PFIC2) is a rare genetic disease that affects the liver. It is caused by mutations in the ABCB11 gene. This gene provides instructions for making a protein called bile salt export pump (BSEP), which is responsible for transporting bile acids out of liver cells. When the ABCB11 gene is mutated, the BSEP protein is not produced correctly, resulting in a buildup of bile acids in liver cells. This buildup can lead to liver damage and other complications.

Symptoms of PFIC2

The symptoms of PFIC2 can vary from person to person, but they typically begin in infancy or early childhood. The most common symptoms include:

• Jaundice (yellowing of the skin and eyes)
• Itching
• Pale stools
• Enlarged liver and spleen
• Growth failure
• Osteoporosis
• Portal hypertension
• Liver failure

Diagnosis of PFIC2

Diagnosing PFIC2 can be challenging, as its symptoms can be similar to those of other liver disorders. However, genetic testing can confirm the diagnosis. The ABCB11 Gene Cholestasis Progressive Intrahepatic Type 2 NGS Genetic Test is a highly accurate test that can identify mutations in the ABCB11 gene that cause PFIC2.

The ABCB11 Gene Cholestasis Progressive Intrahepatic Type 2 NGS Genetic Test

The ABCB11 Gene Cholestasis Progressive Intrahepatic Type 2 NGS Genetic Test is a next-generation sequencing (NGS) test that analyzes the entire ABCB11 gene. This test can identify mutations that cause PFIC2 with a high degree of accuracy.

The test is performed using a small blood sample, which is sent to a laboratory for analysis. Results are typically available within 2-3 weeks.

Cost of the Test

The cost of the ABCB11 Gene Cholestasis Progressive Intrahepatic Type 2 NGS Genetic Test is INR 20,000.

Conclusion

PFIC2 is a rare genetic disorder that can cause serious liver damage and other complications. The ABCB11 Gene Cholestasis Progressive Intrahepatic Type 2 NGS Genetic Test is a highly accurate test that can identify mutations in the ABCB11 gene that cause PFIC2. If you or a loved one is experiencing symptoms of PFIC2, speak to a healthcare provider about the possibility of genetic testing.

At DNA Labs India, we offer a wide range of genetic tests, including the ABCB11 Gene Cholestasis Progressive Intrahepatic Type 2 NGS Genetic Test. Contact us today to learn more.

 Note: We offer free home sample collection for online bookings for ABCB11 Gene Cholestasis progressive intrahepatic type 2 NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.