Short Description

NGS genetic DNA test detecets for variant and mutation detection in ABCC8 gene for Diabetes mellitus, noninsulin-dependent

PreTest Information

Clinical History of Patient who is going for ABCC8 Gene Diabetes mellitus, noninsulin-dependent NGS Genetic DNA Test A Genetic Counselling session to draw a pedigree chart of family members affected with Diabetes mellitus, noninsulin-dependent

Detail Description

ABCC8 Gene Diabetes Mellitus, Non-Insulin-Dependent NGS Genetic DNA Test Cost INR: 20000 Symptoms Diagnosis

Diabetes Mellitus is a chronic disease that affects millions of people worldwide. It is a metabolic disorder that occurs when the body is unable to produce or effectively use insulin, resulting in high blood sugar levels. Diabetes can be classified into two types: Type 1 and Type 2. Type 1 diabetes is caused by the destruction of insulin-producing cells in the pancreas, whereas Type 2 diabetes is caused by insulin resistance.

Non-insulin-dependent diabetes, also known as Type 2 diabetes, is the most common form of diabetes. It is caused by a combination of genetic and environmental factors. One of the genes that have been associated with Type 2 diabetes is the ABCC8 gene.

The ABCC8 Gene and Type 2 Diabetes

The ABCC8 gene provides instructions for making a protein called sulfonylurea receptor 1 (SUR1). SUR1 plays a crucial role in the insulin-producing cells of the pancreas, where it helps to regulate insulin secretion. Mutations in the ABCC8 gene can disrupt the function of SUR1, leading to impaired insulin secretion and increased blood sugar levels.

Research has shown that mutations in the ABCC8 gene are associated with an increased risk of developing Type 2 diabetes. Individuals with mutations in this gene may have a higher likelihood of developing diabetes at a younger age and with a more severe clinical presentation.

Symptoms of Type 2 Diabetes

The symptoms of Type 2 diabetes can be subtle and develop gradually over time. Some common symptoms include:

• Increased thirst
• Frequent urination
• Increased hunger
• Blurred vision
• Fatigue
• Slow-healing wounds

If you are experiencing any of these symptoms, it is important to speak with your healthcare provider for further evaluation.

Diagnosis of Type 2 Diabetes

The diagnosis of Type 2 diabetes is typically made through a combination of blood tests and physical examination. Your healthcare provider may perform a fasting blood glucose test, an oral glucose tolerance test, or a hemoglobin A1C test to assess your blood sugar levels. They may also perform a physical examination to check for signs of complications associated with diabetes, such as neuropathy or retinopathy.

NGS Genetic DNA Test for ABCC8 Gene

NGS Genetic DNA testing is a highly specialized diagnostic test that can identify mutations in the ABCC8 gene. This test can help to identify individuals who may be at increased risk of developing Type 2 diabetes. The cost of this test is INR 20,000.

If you have a family history of Type 2 diabetes or are experiencing symptoms associated with diabetes, speak with your healthcare provider about the possibility of undergoing NGS Genetic DNA testing for the ABCC8 gene.

Conclusion

Type 2 diabetes is a chronic disease that can have serious health consequences if left untreated. Mutations in the ABCC8 gene have been associated with an increased risk of developing Type 2 diabetes. If you are experiencing symptoms associated with diabetes or have a family history of the disease, it is important to speak with your healthcare provider about the possibility of undergoing NGS Genetic DNA testing for the ABCC8 gene.

At DNA Labs India, we offer NGS Genetic DNA testing for the ABCC8 gene at a cost of INR 20,000. Our highly trained and experienced staff can provide you with the information and support you need to make informed decisions about your health.

Contact us today to learn more about our services and how we can help you.