Short Description

ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 motif, 13) is an enzyme that specifically cleaves usually large von Willebrand Factor (VWF) multimers. If activity of ADAMTS13 is decreased, either because of an inherited mutation within ADAMTS13 gene, or because of the development of an autoantibody, the accumulation of ultra large VWF multimers may cause microvascular thrombosis due to platelet aggregation and produce syndrome of Thrombotic Thrombocytopenic Purpura (TTP). This assay is performed to confirm TTP diagnosis and may also be used in the prediction of TTP relapse.

PreTest Information

Overnight fasting is preferred. Duly filled Coagulation Requisition Form (Form 15) is mandatory.

Detail Description

ADAMTS13 Activity Test Cost in India - DNA Labs India

ADAMTS13 is an enzyme that plays a key role in preventing blood clots. Low levels of this enzyme can lead to a condition called thrombotic thrombocytopenic purpura (TTP), which is characterized by blood clots in small blood vessels throughout the body.

The ADAMTS13 activity test measures the level of this enzyme in the blood. This test is usually ordered when a patient exhibits symptoms of TTP, such as:

• Fever
• Fatigue
• Headache
• Confusion
• Shortness of breath
• Chest pain
• Weakness
• Yellowing of the skin and eyes (jaundice)
• Bleeding under the skin or from the gums or nose
• Dark urine
• Decreased urine output

If you experience any of these symptoms, it is important to seek medical attention immediately. TTP can be life-threatening if left untreated.

The ADAMTS13 activity test is performed by drawing a blood sample from the patient. The sample is then sent to a laboratory for analysis. The cost of this test in India is typically around INR 26,000.

If the test results show low levels of ADAMTS13, additional testing may be necessary to confirm a diagnosis of TTP. Treatment for TTP usually involves plasma exchange, which is a process that removes the patient's plasma and replaces it with donor plasma that contains normal levels of ADAMTS13. Other treatments may include corticosteroids, immunosuppressants, and blood transfusions.

At DNA Labs India, we offer reliable and affordable ADAMTS13 activity testing services. Our team of experienced professionals uses state-of-the-art technology to provide accurate results. If you are experiencing symptoms of TTP or have been diagnosed with this condition, contact us today to schedule a test.