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ALPL Gene Hypophosphatasia, infantile NGS Genetic Test Cost

Original price was: ₹28,000.Current price is: ₹20,000.

-29%

NGS Genetic Test detecets for variant and mutation detection in ALPL gene for Hypophosphatasia, infantile

Free Sample collection at your home for all online bookings

  • 100% Accurate Test Results
  • Book test before 2.30pm for same day Sample Collection
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ALPL Gene Hypophosphatasia: Symptoms, Diagnosis, and NGS Genetic Test Cost

Hypophosphatasia is a rare genetic disorder that affects the development and maintenance of bones and teeth. The disease is caused by mutations in the ALPL gene, which encodes an enzyme called tissue-nonspecific alkaline phosphatase (TNSALP). TNSALP is responsible for breaking down a molecule called inorganic pyrophosphate, which is a natural inhibitor of bone mineralization. When TNSALP is deficient, inorganic pyrophosphate accumulates and interferes with bone mineralization, resulting in weak and brittle bones.

Symptoms of Hypophosphatasia

The symptoms of hypophosphatasia can vary widely depending on the severity of the disease. In some cases, the disease is so mild that it goes unnoticed, while in others, it can be life-threatening. The most common symptoms of hypophosphatasia include:

  • Soft or weak bones that are prone to fractures
  • Dental problems, such as premature loss of teeth and delayed tooth formation
  • Muscle weakness and pain
  • Short stature
  • Breathing problems
  • Seizures
  • Developmental delays

Diagnosis of Hypophosphatasia

Diagnosis of hypophosphatasia can be challenging because the symptoms can be similar to other bone disorders. However, there are several tests that can help diagnose the disease, including:

  • Blood tests to measure levels of ALP and inorganic pyrophosphate
  • X-rays to check for abnormalities in bone structure
  • Genetic testing to identify mutations in the ALPL gene
  • Enzyme activity testing to measure TNSALP activity

NGS Genetic Test Cost

Next-generation sequencing (NGS) is a powerful tool that can be used to analyze the DNA sequence of the ALPL gene and identify mutations that cause hypophosphatasia. The cost of NGS Genetic Testing for hypophosphatasia in India is approximately INR 20,000. This test can provide valuable information for patients and their families, including:

  • Confirmation of a diagnosis
  • Predictive testing for family members
  • Identification of carriers
  • Guidance for reproductive decisions
  • Insight into disease severity and prognosis

Conclusion

Hypophosphatasia is a rare genetic disorder that can cause significant health problems if left untreated. Early diagnosis and treatment can improve outcomes for patients with the disease. NGS Genetic Testing can provide valuable information for patients and their families and is a cost-effective way to confirm a diagnosis and guide treatment decisions.

At DNA Labs India, we offer NGS Genetic Testing for hypophosphatasia and other genetic disorders. Our team of experts uses the latest technology and techniques to provide accurate and timely results. Contact us today to learn more about our services.

Test NameALPL Gene Hypophosphatasia, infantile NGS Genetic Test
Sample typeBlood or Extracted DNA or One drop Blood on FTA Card
Test typeGeneral Physician
Pre-test InformationClinical History of Patient who is going for ALPL Gene Hypophosphatasia, infantile NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with Hypophosphatasia, infantile
DiseaseMetabolic Disorders
MethodNGS Technology
PurposeNULL
PreparationAmbient Room Temperature
FastingClinical History of Patient who is going for ALPL Gene Hypophosphatasia, infantile NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with Hypophosphatasia, infantile
Get Reports3 to 4 Weeks
Test PriceINR ₹ 20000

 Note: We offer free home sample collection for online bookings for ALPL Gene Hypophosphatasia, infantile NGS Genetic Test and the test costs special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.