AMELX Gene and Amelogenesis Imperfecta Type 1E: Symptoms, Diagnosis, and NGS Genetic Test Cost
Amelogenesis Imperfecta Type 1E is a rare genetic disorder that affects the development of tooth enamel. It is caused by mutations in the AMELX gene, which provides instructions for making a protein called amelogenin. This protein is essential for the formation and mineralization of tooth enamel.
Symptoms
The symptoms of Amelogenesis Imperfecta Type 1E can vary depending on the severity of the mutation. Some common symptoms include:
- Thin, weak, or discolored enamel
- Rough or pitted enamel surface
- Increased susceptibility to tooth decay and erosion
- Delayed eruption of permanent teeth
- Abnormal tooth shape and size
People with Amelogenesis Imperfecta Type 1E may also experience sensitivity to hot or cold temperatures and have difficulty chewing or biting.
Diagnosis
Diagnosis of Amelogenesis Imperfecta Type 1E typically involves a thorough dental exam, including a review of the patient’s medical and family history. X-rays and other imaging tests may also be used to evaluate the teeth and jaw. Genetic testing can confirm the presence of mutations in the AMELX gene.
NGS Genetic Test Cost
NGS Genetic Testing is a highly accurate and efficient way to identify mutations in the AMELX gene. At DNA Labs India, we offer this test for a cost of INR 20,000. This includes a comprehensive analysis of the patient’s DNA sample, as well as a detailed report of the results.
NGS Genetic Testing can be particularly useful for families with a history of Amelogenesis Imperfecta Type 1E, as it can help identify carriers of the mutation and guide family planning decisions. It can also be helpful for individuals with unexplained dental problems that may be related to genetic factors.
Conclusion
Amelogenesis Imperfecta Type 1E is a rare genetic disorder that can have significant impacts on dental health and quality of life. With the help of modern genetic testing technologies, however, it is possible to identify mutations in the AMELX gene and develop targeted treatment plans. If you or a loved one is experiencing symptoms of Amelogenesis Imperfecta Type 1E, consider talking to a genetic counselor or dental professional about the benefits of genetic testing.
| Test Name | AMELX Gene Amelogenesis imperfecta type 1E NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Dermatologist |
| Pre-test Information | Clinical History of Patient who is going for AMELX Gene Amelogenesis imperfecta type 1E NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with AMELX Gene Amelogenesis imperfecta type 1E NGS Genetic Test gene AMELX |
| Disease | Osteology Dermatology Immunology Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for AMELX Gene Amelogenesis imperfecta type 1E NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with AMELX Gene Amelogenesis imperfecta type 1E NGS Genetic Test gene AMELX |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for AMELX Gene Amelogenesis imperfecta type 1E NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
