APOE Gene Sea-blue histiocyte disease NGS Genetic Test Cost INR:20000 Symptoms Diagnosis
Sea-blue histiocyte disease is a rare genetic disorder characterized by the accumulation of lipid-laden histiocytes, which gives the cells a blue appearance. It is caused by mutations in the APOE gene, which encodes the protein apolipoprotein E. This protein plays a crucial role in lipid metabolism, and mutations in the APOE gene can disrupt this process and lead to the accumulation of lipids in various tissues.
NGS Genetic Testing is a powerful tool for diagnosing sea-blue histiocyte disease. This test uses next-generation sequencing technology to analyze the patient’s DNA and identify any mutations in the APOE gene. It can also be used to identify other genetic variants that may be contributing to the patient’s symptoms.
Symptoms of Sea-blue Histiocyte Disease
The symptoms of sea-blue histiocyte disease can vary widely depending on the severity of the condition and the tissues affected by lipid accumulation. Some common symptoms include:
- Hepatosplenomegaly (enlarged liver and spleen)
- Neurological symptoms, such as seizures and cognitive impairment
- Thrombocytopenia (low platelet count)
- Anemia (low red blood cell count)
- Bone pain and fractures
- Eye abnormalities, such as retinal degeneration
Because sea-blue histiocyte disease is a rare disorder, many of these symptoms are also associated with other conditions. Therefore, a definitive diagnosis requires genetic testing.
Diagnosis of Sea-blue Histiocyte Disease
NGS Genetic Testing is the most reliable method for diagnosing sea-blue histiocyte disease. This test can detect mutations in the APOE gene with high accuracy, allowing for an early and accurate diagnosis.
If a patient is suspected of having sea-blue histiocyte disease, their doctor will likely order an NGS Genetic Test. This test typically involves taking a blood or saliva sample from the patient and sending it to a specialized laboratory for analysis. The results of the test can take several weeks to come back, but they can provide crucial information for the patient and their healthcare team.
Cost of NGS Genetic Testing for Sea-blue Histiocyte Disease
The cost of NGS Genetic Testing for sea-blue histiocyte disease can vary depending on the specific laboratory and healthcare provider. However, in India, the cost of this test typically ranges from INR 15,000 to INR 25,000.
While this cost may seem high, it is important to remember that an accurate diagnosis can help patients receive appropriate treatment and avoid unnecessary procedures and medications. Furthermore, some healthcare providers may offer financial assistance or payment plans to help patients afford genetic testing.
Conclusion
Sea-blue histiocyte disease is a rare genetic disorder that can cause a range of symptoms, including neurological problems, hepatosplenomegaly, and anemia. NGS Genetic Testing is the most reliable method for diagnosing this condition, and it typically costs between INR 15,000 and INR 25,000 in India. If you or a loved one is experiencing symptoms of sea-blue histiocyte disease, it is important to talk to a healthcare provider and consider genetic testing as a potential diagnostic tool.
| Test Name | APOE Gene Sea-blue histiocyte disease NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Hematologist |
| Pre-test Information | Clinical History of Patient who is going for APOE Gene Sea-blue histiocyte disease NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with APOE Gene Sea-blue histiocyte disease NGS Genetic Test gene APOE |
| Disease | Hematology |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for APOE Gene Sea-blue histiocyte disease NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with APOE Gene Sea-blue histiocyte disease NGS Genetic Test gene APOE |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for APOE Gene Sea-blue histiocyte disease NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
