Understanding ATP8B1 Gene Cholestasis: Symptoms, Diagnosis, and NGS Genetic Test Cost in India

ATP8B1 Gene Cholestasis, also known as Benign Recurrent Intrahepatic Cholestasis (BRIC), is a rare genetic condition that affects the liver’s ability to produce bile, leading to recurrent episodes of cholestasis. The condition is caused by mutations in the ATP8B1 gene, which encodes for a protein that plays a crucial role in bile secretion.

Symptoms of ATP8B1 Gene Cholestasis

The symptoms of ATP8B1 Gene Cholestasis typically appear in childhood or early adulthood and may include:

• Jaundice (yellowing of the skin and eyes)
• Itching
• Fatigue
• Abdominal pain
• Dark urine
• Pale stools

Episodes of cholestasis may last for a few days to several weeks and can recur throughout a person’s life. In between episodes, liver function may return to normal, and there may be no symptoms.

Diagnosis of ATP8B1 Gene Cholestasis

Diagnosis of ATP8B1 Gene Cholestasis involves a combination of medical history, physical examination, and laboratory tests. Your doctor may order:

• Blood tests to check liver function and levels of bilirubin
• Imaging tests, such as an ultrasound or MRI, to examine the liver and bile ducts
• A liver biopsy to examine liver tissue under a microscope

A genetic test may also be performed to identify mutations in the ATP8B1 gene. This test can confirm a diagnosis of ATP8B1 Gene Cholestasis and determine if other family members are at risk of developing the condition.

NGS Genetic Test Cost in India

NGS (Next-Generation Sequencing) Genetic Test is a cutting-edge technology that allows for the rapid and accurate sequencing of DNA. This test can be used to identify mutations in the ATP8B1 gene and other genes associated with liver disease.

In India, the cost of NGS Genetic Test for ATP8B1 Gene Cholestasis ranges from INR 15,000 to INR 25,000, depending on the laboratory and location. This cost may or may not include counseling and interpretation of test results.

Conclusion

ATP8B1 Gene Cholestasis is a rare genetic condition that can cause recurrent episodes of cholestasis. Symptoms may include jaundice, itching, fatigue, and abdominal pain. Diagnosis involves a combination of medical history, physical examination, and laboratory tests, including a genetic test. NGS Genetic Test is a cutting-edge technology that can identify mutations in the ATP8B1 gene and other genes associated with liver disease. The cost of this test in India ranges from INR 15,000 to INR 25,000, depending on the laboratory and location.

If you or a loved one are experiencing symptoms of ATP8B1 Gene Cholestasis, consult with a healthcare provider to determine the best course of action.

For more information on NGS Genetic Test, contact DNA Labs India today.

 Note: We offer free home sample collection for online bookings for ATP8B1 Gene Cholestasis, benign recurrent intrahepatic NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.