Short Description

BCR-ABL is a fusion gene formed by the rearrangement of breakpoint cluster region (BCR) on chromosome 22 with the ABL protooncogene on chromosome 9 leading to the formation of Philadelphia chromosome. This rearrangement is seen in almost 95% patients with CML. The Quantitative assay helps in the management of the disease and monitors effect of therapy.

PreTest Information

Duly filled MRD Requisition Form (Form 22) with historical data is mandatory.

Detail Description

BCR-ABL QUANTITATIVE MRD MONITOR Test Cost INR:8200 Symptoms Diagnosis

DNA Labs India offers the BCR-ABL QUANTITATIVE MRD MONITOR test at a cost of INR 8200. This test is used to monitor the response to treatment in patients with chronic myeloid leukemia (CML). The test measures the amount of BCR-ABL transcripts in the blood, which is a marker for the disease. The test is used to detect minimal residual disease (MRD) and to monitor the effectiveness of treatment.

What is Chronic Myeloid Leukemia?

Chronic myeloid leukemia (CML) is a type of cancer that affects the blood and bone marrow. It is caused by a genetic mutation that leads to the production of an abnormal protein called BCR-ABL. This protein causes the bone marrow to produce too many white blood cells, which can lead to a range of symptoms.

What are the Symptoms of CML?

The symptoms of CML can vary from person to person, but may include:

• Fatigue
• Weight loss
• Night sweats
• Fever
• Abdominal pain
• Bone pain
• Enlarged spleen
• Enlarged liver

How is CML Diagnosed?

CML is usually diagnosed through a combination of blood tests and bone marrow biopsy. The blood tests may include a complete blood count (CBC) and a test to measure the amount of BCR-ABL transcripts in the blood. The bone marrow biopsy involves taking a small sample of bone marrow and examining it under a microscope.

What is the BCR-ABL QUANTITATIVE MRD MONITOR Test?

The BCR-ABL QUANTITATIVE MRD MONITOR test is used to monitor the response to treatment in patients with CML. The test measures the amount of BCR-ABL transcripts in the blood, which is a marker for the disease. The test is used to detect minimal residual disease (MRD) and to monitor the effectiveness of treatment.

How is the Test Performed?

The BCR-ABL QUANTITATIVE MRD MONITOR test is a blood test. A small sample of blood is taken from the patient and sent to the laboratory for analysis.

What is the Cost of the Test?

The cost of the BCR-ABL QUANTITATIVE MRD MONITOR test at DNA Labs India is INR 8200.

Conclusion

The BCR-ABL QUANTITATIVE MRD MONITOR test is a valuable tool for monitoring the response to treatment in patients with CML. The test measures the amount of BCR-ABL transcripts in the blood, which is a marker for the disease. The test is used to detect minimal residual disease (MRD) and to monitor the effectiveness of treatment. DNA Labs India offers the test at a cost of INR 8200.