BDNF Gene and Central Hypoventilation Syndrome: Symptoms, Diagnosis, and NGS Genetic Test Cost
Central hypoventilation syndrome (CHS) is a rare genetic disorder that affects breathing during sleep and wakefulness. It is also known as Ondine’s curse, named after a mythological character who was cursed to forget to breathe. CHS is caused by mutations in the BDNF gene, which provides instructions for making a protein that helps to regulate breathing. In this blog, we will discuss the symptoms, diagnosis, and NGS Genetic Test cost for CHS.
Symptoms of CHS
The hallmark symptom of CHS is hypoventilation, which is an abnormally slow or shallow breathing pattern. This can occur during sleep or wakefulness and can lead to low oxygen levels in the blood (hypoxemia) and high carbon dioxide levels (hypercapnia). Other symptoms of CHS include:
- Difficulty breathing
- Shortness of breath
- Fatigue
- Difficulty staying awake
- Difficulty eating and swallowing
- Delayed growth and development
CHS can also cause sudden death in some cases, particularly during sleep. Therefore, it is important to diagnose and manage the condition as early as possible.
Diagnosis of CHS
CHS is diagnosed based on a combination of clinical features and genetic testing. The clinical features may include hypoventilation, abnormal breathing patterns, and low oxygen levels in the blood. Genetic testing can confirm the diagnosis by identifying mutations in the BDNF gene.
NGS Genetic Testing is a powerful tool for identifying genetic mutations associated with CHS. NGS stands for next-generation sequencing, which is a high-throughput sequencing technology that can analyze large amounts of DNA in a short amount of time. NGS testing can identify mutations in the BDNF gene with high accuracy and sensitivity, making it a valuable tool for diagnosing CHS.
NGS Genetic Test Cost
The cost of NGS Genetic Testing for CHS in India is approximately INR 20,000. This cost may vary depending on the specific testing laboratory and the extent of the genetic analysis performed. However, NGS testing is generally considered to be a cost-effective and efficient method for diagnosing CHS.
Conclusion
Central hypoventilation syndrome is a rare genetic disorder that can cause breathing difficulties and other symptoms. It is caused by mutations in the BDNF gene, which can be identified through NGS Genetic Testing. The cost of this testing in India is around INR 20,000, making it a valuable tool for diagnosing and managing CHS. If you or someone you know is experiencing symptoms of CHS, it is important to seek medical attention and consider genetic testing to confirm the diagnosis.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for BDNF Gene Central hypoventilation syndrome, congenital NGS Genetic Test
| Test Name | BDNF Gene Central hypoventilation syndrome, congenital NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Pediatrics |
| Pre-test Information | Clinical History of Patient who is going for BDNF Gene Central hypoventilation syndrome, congenital NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with BDNF Gene Central hypoventilation syndrome, congenital NGS Genetic Test gene BDNF |
| Disease | Dysmorphology |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for BDNF Gene Central hypoventilation syndrome, congenital NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with BDNF Gene Central hypoventilation syndrome, congenital NGS Genetic Test gene BDNF |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for BDNF Gene Central hypoventilation syndrome, congenital NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
