CALR Gene and Schizophrenia: Symptoms, Diagnosis, and NGS Genetic Test Cost in India

Schizophrenia is a complex mental disorder that affects millions of people worldwide. It is a chronic condition that impacts a person’s ability to think, feel, and behave clearly. Although the exact causes of schizophrenia are not yet known, studies have found that genetics plays a significant role in its development. One of the genes that have been associated with schizophrenia is the CALR gene.

What is the CALR gene?

The CALR gene, also known as the calreticulin gene, is located on chromosome 19 and encodes the calreticulin protein. This protein is involved in various cellular processes, including protein folding, calcium homeostasis, and immune response. Mutations in the CALR gene have been linked to several diseases, including cancer and blood disorders.

CALR gene and schizophrenia

Recent studies have found that the CALR gene may also play a role in the development of schizophrenia. A study conducted in 2019 found that mutations in the CALR gene were significantly associated with an increased risk of schizophrenia. The researchers suggested that the mutations may disrupt the protein’s function, leading to altered calcium signaling and neural connectivity in the brain, which could contribute to the development of schizophrenia.

Symptoms of schizophrenia

Schizophrenia is a complex disorder that can manifest in various ways. The symptoms of schizophrenia are divided into three categories: positive symptoms, negative symptoms, and cognitive symptoms.

• Positive symptoms: These are symptoms that involve an excess or distortion of normal functions. They include hallucinations, delusions, disorganized speech, and disorganized behavior.
• Negative symptoms: These are symptoms that involve a loss or decrease in normal functions. They include a lack of emotion, social withdrawal, and reduced motivation.
• Cognitive symptoms: These are symptoms that involve changes in cognitive processes, such as attention, memory, and problem-solving.

Diagnosis of schizophrenia

Diagnosing schizophrenia is a complex process that involves a thorough evaluation of a person’s symptoms, medical history, and family history. A mental health professional, such as a psychiatrist, will typically conduct the evaluation and may use various tools, such as the Diagnostic and Statistical Manual of Mental Disorders (DSM-5), to aid in the diagnosis.

NGS Genetic Test for CALR gene mutations

NGS (Next Generation Sequencing) Genetic Test is a highly advanced test that can detect mutations in the CALR gene. This test is useful in identifying individuals who may be at an increased risk of developing schizophrenia due to CALR gene mutations. The test involves sequencing the entire CALR gene to identify any mutations that may be present.

Cost of NGS Genetic Test for CALR gene mutations in India

The cost of the NGS Genetic Test for CALR gene mutations in India can vary depending on the laboratory and location. On average, the cost of the test is around INR 20,000.

Conclusion

Schizophrenia is a complex disorder that can have a significant impact on a person’s life. While the exact causes of schizophrenia are not yet known, genetics is believed to play a significant role in its development. The CALR gene has been found to be associated with an increased risk of schizophrenia, and the NGS Genetic Test can help identify individuals who may be at risk due to CALR gene mutations. If you or a loved one is experiencing symptoms of schizophrenia, it is essential to seek help from a mental health professional.

 Note: We offer free home sample collection for online bookings for CALR Gene Schizophrenia, CALR related NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.