CD46 Gene Hemolytic Uremic Syndrome: Symptoms, Diagnosis, and NGS Genetic Test Cost
CD46 gene hemolytic uremic syndrome (HUS) is a rare genetic disorder that affects the blood vessels and can lead to kidney failure. It is also known as atypical type 2 HUS because it is caused by mutations in the CD46 gene, which plays a role in regulating the immune system and protecting cells from damage.
NGS Genetic Testing can help diagnose CD46 gene HUS by identifying mutations in the CD46 gene. This test uses next-generation sequencing technology to analyze DNA samples and detect genetic changes that may be causing the disorder.
Symptoms of CD46 Gene Hemolytic Uremic Syndrome
The symptoms of CD46 gene HUS can vary depending on the severity of the disorder. Some common symptoms include:
- Bloody diarrhea
- Abdominal pain
- Fever
- Fatigue
- Reduced urine output
- Swelling in the legs, ankles, or feet
In severe cases, CD46 gene HUS can lead to kidney failure, which may require dialysis or a kidney transplant.
Diagnosis of CD46 Gene Hemolytic Uremic Syndrome
Diagnosing CD46 gene HUS can be challenging because it is a rare disorder and its symptoms can be similar to other conditions. Doctors may use a combination of tests, including:
- Blood tests to check for anemia and low platelet count
- Urine tests to check for protein and blood in the urine
- Genetic testing to check for mutations in the CD46 gene
A genetic test can confirm a diagnosis of CD46 gene HUS and help doctors develop a treatment plan.
NGS Genetic Test Cost at DNA Labs India
The cost of an NGS Genetic Test for CD46 gene HUS at DNA Labs India is INR 20,000. This test can help diagnose the disorder and guide treatment decisions, potentially improving outcomes for patients.
If you or a loved one is experiencing symptoms of CD46 gene HUS, talk to your doctor about genetic testing and how it can help. DNA Labs India offers reliable and affordable NGS Genetic Testing services to help diagnose rare genetic disorders like CD46 gene HUS.
The CD46 gene encodes a protein known as membrane cofactor protein (MCP), which plays a role in regulating the complement system, a part of the immune system involved in fighting infections and clearing out damaged cells.
Mutations in the CD46 gene can lead to susceptibility to Atypical Hemolytic Uremic Syndrome Type 2. These mutations can disrupt the normal regulatory function of the complement system, leading to excessive activation and inflammation in the blood vessels.
NGS (Next-Generation Sequencing) Genetic Tests are used to analyze the DNA sequence of genes like CD46 to identify any mutations or variants that may be associated with susceptibility to Atypical Hemolytic Uremic Syndrome Type 2.
If you or someone you know is considering genetic testing for Atypical Hemolytic Uremic Syndrome related to the CD46 gene, I recommend consulting with a nephrologist (kidney specialist), a medical geneticist, or a genetic counselor. They can provide accurate and current information about the condition, the implications of genetic testing, and any available treatment options. Medical knowledge can evolve, so it’s important to rely on expert guidance for the latest information.
| Test Name | CD46 Gene Hemolytic uremic syndrome, atypical type 2, susceptibility to NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | General Physician |
| Pre-test Information | Clinical History of Patient who is going for CD46 Gene Hemolytic uremic syndrome, atypical type 2, susceptibility to NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CD46 Gene Hemolytic uremic syndrome, atypical type 2, susceptibility to NGS Genetic Test gene CD46 |
| Disease | Hepatology Nephrology Endocrinology Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for CD46 Gene Hemolytic uremic syndrome, atypical type 2, susceptibility to NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with CD46 Gene Hemolytic uremic syndrome, atypical type 2, susceptibility to NGS Genetic Test gene CD46 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for CD46 Gene Hemolytic uremic syndrome, atypical type 2, susceptibility to NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
