DNAJC5 Gene Ceroid Lipofuscinosis Neuronal Type 4 NGS Genetic Test: Symptoms, Diagnosis and Cost
DNAJC5 gene ceroid lipofuscinosis neuronal type 4 (CLN4) is a rare genetic disorder that affects the nervous system. It is caused by mutations in the DNAJC5 gene, which provides instructions for making a protein called cysteine-string protein alpha (CSPα). This protein is important for the normal functioning of nerve cells in the brain and spinal cord.
Symptoms of CLN4
The symptoms of CLN4 can vary widely, but often include:
- Seizures
- Loss of muscle control
- Visual impairment
- Behavioral changes
- Dementia
- Speech problems
These symptoms usually begin in childhood, typically between the ages of 4 and 7. The disease is progressive, meaning that symptoms worsen over time, and it often leads to premature death.
Diagnosis of CLN4
Diagnosing CLN4 can be challenging because it is a rare disease and symptoms can be similar to those of other neurological disorders. However, doctors may use a combination of tests to diagnose CLN4, including:
- Physical exam
- Medical history
- Neurological exam
- Electroencephalogram (EEG)
- Magnetic resonance imaging (MRI)
- Genetic testing, such as NGS Genetic Testing
NGS Genetic Test for CLN4
Next-generation sequencing (NGS) Genetic Testing is a powerful tool for diagnosing CLN4. This type of testing can analyze multiple genes simultaneously, including the DNAJC5 gene, which is responsible for CLN4. NGS Genetic Testing can provide a definitive diagnosis of CLN4, which can help doctors develop an appropriate treatment plan.
Cost of NGS Genetic Test for CLN4
The cost of NGS Genetic Testing for CLN4 can vary depending on the provider, location, and other factors. In India, the cost of NGS Genetic Testing for CLN4 is typically around INR 20,000. However, it is important to check with the provider to confirm the cost and any additional fees that may apply.
Conclusion
CLN4 is a rare genetic disorder that can cause a range of neurological symptoms. NGS Genetic Testing can provide a definitive diagnosis of CLN4, which can help doctors develop an appropriate treatment plan. The cost of NGS Genetic Testing for CLN4 in India is typically around INR 20,000. If you or a loved one is experiencing symptoms of CLN4, it is important to speak with a doctor as soon as possible.
At DNA Labs India, we offer NGS Genetic Testing for CLN4 and other genetic disorders. Our testing is accurate, reliable, and affordable, and our team of experts is dedicated to helping you get the answers you need. Contact us today to learn more.
| Test Name | DNAJC5 Gene Ceroid lipofuscinosis neuronal type 4 NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | General Physician |
| Pre-test Information | Clinical History of Patient who is going for DNAJC5 Gene Ceroid lipofuscinosis neuronal type 4 NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with Ceroid lipofuscinosis neuronal type 4 |
| Disease | Metabolic Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for DNAJC5 Gene Ceroid lipofuscinosis neuronal type 4 NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with Ceroid lipofuscinosis neuronal type 4 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for DNAJC5 Gene Ceroid lipofuscinosis neuronal type 4 NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
