GPR101 Gene Acromegaly – Predisposition, Symptoms, Diagnosis, and Cost of NGS Genetic Test
Acromegaly is a rare condition that occurs when the pituitary gland produces too much growth hormone, resulting in abnormal growth and enlargement of bones and tissues. While most cases of acromegaly are sporadic, some individuals may be predisposed to the condition due to a germline mutation in the GPR101 gene.
What is the GPR101 Gene?
The GPR101 gene is located on chromosome Xq26.3 and encodes for a G protein-coupled receptor that plays a role in regulating the release of growth hormone. A germline mutation in this gene can result in the overproduction of growth hormone, leading to acromegaly.
Symptoms of Acromegaly
Acromegaly develops slowly and may take several years to become noticeable. The symptoms of acromegaly include:
- Enlargement of the hands, feet, and facial features
- Thickening of the skin
- Deepening of the voice
- Joint pain and stiffness
- Increased sweating and body odor
- Sleep apnea
- Headaches
- Visual disturbances
Diagnosis of Acromegaly
The diagnosis of acromegaly involves a combination of physical examination, medical history, and laboratory tests. The following tests may be used to diagnose acromegaly:
- IGF-1 (insulin-like growth factor 1) test
- GH (growth hormone) suppression test
- MRI (magnetic resonance imaging) of the pituitary gland
NGS Genetic Test for GPR101 Mutation
If there is a suspicion of a germline GPR101 mutation causing acromegaly, a Next-Generation Sequencing (NGS) Genetic Test can be performed to confirm the presence of the mutation. This test involves the sequencing of the entire GPR101 gene to identify any mutations. The cost of the NGS Genetic Test for GPR101 mutation is INR 20,000.
Conclusion
Acromegaly is a rare condition that can be caused by a germline mutation in the GPR101 gene. If you or someone you know is experiencing symptoms of acromegaly, it is important to seek medical attention. A diagnosis of acromegaly can be confirmed with laboratory tests, and a Genetic Test for GPR101 mutation can be performed to identify any predisposition to the condition. At DNA Labs India, we offer NGS Genetic Testing for GPR101 mutation at a cost of INR 20,000.
| Test Name | GPR101 Gene Acromegaly, predisposition to, due to germline GPR101 mutation NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | General Physician |
| Pre-test Information | Clinical History of Patient who is going for GPR101 Gene Acromegaly, predisposition to, due to germline GPR101 mutation NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with GPR101 Gene Acromegaly, predisposition to, due to germline GPR101 mutation NGS Genetic Test gene GPR101 |
| Disease | Hepatology Nephrology Endocrinology Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for GPR101 Gene Acromegaly, predisposition to, due to germline GPR101 mutation NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with GPR101 Gene Acromegaly, predisposition to, due to germline GPR101 mutation NGS Genetic Test gene GPR101 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for GPR101 Gene Acromegaly, predisposition to, due to germline GPR101 mutation NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
