Understanding GUSB Gene Mucopolysaccharidosis Type 7 NGS Genetic Test
GUSB Gene Mucopolysaccharidosis Type 7 (MPS VII) is a rare genetic disorder that is characterized by the accumulation of harmful substances in the body. This condition is caused by mutations in the GUSB gene, which is responsible for producing an enzyme called beta-glucuronidase. The lack of this enzyme leads to the buildup of a substance called glycosaminoglycans (GAGs) in the body, which can cause a range of symptoms and complications.
Symptoms of GUSB Gene Mucopolysaccharidosis Type 7
The symptoms of MPS VII can vary widely from person to person, and can range from mild to severe. Some of the most common symptoms include:
- Developmental delays
- Joint stiffness and pain
- Enlarged liver and spleen
- Facial abnormalities
- Heart valve abnormalities
- Respiratory problems
- Neurological problems
- Vision and hearing loss
Many people with MPS VII also have intellectual disabilities and may experience behavioral problems such as hyperactivity and aggression.
Diagnosing GUSB Gene Mucopolysaccharidosis Type 7
Diagnosing MPS VII can be challenging because the symptoms can be similar to those of other conditions. However, there are a number of tests that can be used to help diagnose the condition, including:
- Physical exams to check for physical abnormalities
- Blood and urine tests to look for high levels of GAGs
- Genetic testing to identify mutations in the GUSB gene
- Enzyme activity tests to measure beta-glucuronidase activity
NGS Genetic Test for GUSB Gene Mucopolysaccharidosis Type 7
The NGS Genetic Test is a highly accurate and reliable test that can be used to identify mutations in the GUSB gene. This test uses next-generation sequencing (NGS) technology to analyze the entire gene, which allows for a more comprehensive analysis of potential mutations.
The NGS Genetic Test is a non-invasive test that can be performed using a simple blood sample. The cost of the test is INR 20,000, and it typically takes several weeks to receive the results.
Conclusion
GUSB Gene Mucopolysaccharidosis Type 7 is a rare genetic disorder that can cause a range of symptoms and complications. While diagnosing the condition can be challenging, the NGS Genetic Test is a highly accurate and reliable test that can help identify mutations in the GUSB gene. If you or a loved one is experiencing symptoms of MPS VII, it is important to speak with a healthcare provider to discuss testing options and potential treatment options.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for GUSB Gene Mucopolysaccharidosis type 7 NGS Genetic Test
| Test Name | GUSB Gene Mucopolysaccharidosis type 7 NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | General Physician |
| Pre-test Information | Clinical History of Patient who is going for GUSB Gene Mucopolysaccharidosis type 7 NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with Mucopolysaccharidosis type 7 |
| Disease | Metabolic Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for GUSB Gene Mucopolysaccharidosis type 7 NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with Mucopolysaccharidosis type 7 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for GUSB Gene Mucopolysaccharidosis type 7 NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
