HBA2 Gene Thalassemia: Symptoms, Diagnosis, and Genetic Testing Cost
Thalassemia is a genetic blood disorder that affects the production of hemoglobin, the protein responsible for carrying oxygen in the blood. There are two main types of thalassemia: alpha and beta. Alpha thalassemia is caused by mutations in the HBA1 and HBA2 genes, which are responsible for producing alpha globin subunits of hemoglobin. In this blog, we will focus on the HBA2 gene and its role in alpha thalassemia.
Symptoms of Alpha Thalassemia
The severity of alpha thalassemia varies depending on the number of gene mutations. People with one or two mutations may not have any symptoms, while those with three or four mutations may experience:
- Anemia
- Fatigue
- Pale skin
- Shortness of breath
- Jaundice
- Bone deformities
- Enlarged spleen
Severe cases of alpha thalassemia can lead to stillbirth or death shortly after birth.
Diagnosis of Alpha Thalassemia
Alpha thalassemia can be diagnosed through a blood test that measures the amount of hemoglobin in the blood and the size of the red blood cells. Additional genetic testing may be necessary to determine the specific mutations in the HBA2 gene.
HBA2 Gene Thalassemia and Genetic Testing
The HBA2 gene is located on chromosome 16 and produces alpha globin subunits of hemoglobin. Mutations in this gene can result in alpha thalassemia, a genetic disorder that affects the production of hemoglobin.
NGS (next-generation sequencing) genetic testing can be used to identify mutations in the HBA2 gene. This type of testing is more comprehensive and can detect multiple mutations at once, making it a valuable tool for diagnosing thalassemia.
Cost of HBA2 Gene Thalassemia NGS Genetic Testing
The cost of NGS genetic testing for HBA2 gene thalassemia varies depending on the provider and location. In India, the cost of this test can range from INR 15,000 to INR 25,000. It is important to consult with a genetic counselor or healthcare provider to determine if genetic testing is necessary and to discuss the potential costs and benefits.
Conclusion
Alpha thalassemia is a genetic blood disorder that can cause anemia, fatigue, and other symptoms. The HBA2 gene plays a critical role in the production of hemoglobin and mutations in this gene can result in alpha thalassemia. NGS genetic testing can be used to diagnose thalassemia and identify specific mutations in the HBA2 gene. The cost of this testing in India can range from INR 15,000 to INR 25,000. If you or a loved one is experiencing symptoms of thalassemia, it is important to consult with a healthcare provider or genetic counselor to discuss potential testing and treatment options.
For more information on genetic testing and thalassemia, contact DNA Labs India.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for HBA2 Gene Thalassemia, alpha NGS Genetic Test
| Test Name | HBA2 Gene Thalassemia, alpha NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Hematologist |
| Pre-test Information | Clinical History of Patient who is going for HBA2 Gene Thalassemia, alpha NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with HBA2 Gene Thalassemia, alpha NGS Genetic Test gene HBA2 |
| Disease | Hematology |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for HBA2 Gene Thalassemia, alpha NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with HBA2 Gene Thalassemia, alpha NGS Genetic Test gene HBA2 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for HBA2 Gene Thalassemia, alpha NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
