Skip to main content
DNA Labs India

Hepatitis B Viral Drug Resistance & Genotyping Test

DNA Labs India | ISO 9001:2015 Certified

Hepatitis B Viral Drug Resistance & Genotyping Test

Short Name: HBV Drug Resistance & Genotyping

Also known as: HBV Genotyping Test, Hepatitis B Resistance Test, HBV Drug Sensitivity Test

Hepatitis B Viral Drug Resistance & Genotyping Test test available at DNA Labs India for ₹13,000. Uses Sequencing on Plasma samples. Results in Report available in 7 days after sample receipt.. Free home collection in 300+ cities across India.

Molecular Diagnostics🏠 Home Collection

🩺 Medically Reviewed By

Overview

To detect drug resistance mutations and determine the genotype of hepatitis B virus for personalized treatment planning and effective management of chronic hepatitis B.

Test Code
714
Price
₹13,000
Sample Type
Plasma
Result Time
Report available in 7 days after sample receipt.
Fasting Required
No
Method
Sequencing
Step 1

Sample Collection

No special preparation required.

Method: Venipuncture

Step 2

Laboratory Analysis

Blood will be drawn from a vein in your arm using a sterile needle.

Step 3

Report Delivery

Apply pressure to the puncture site with a cotton ball to prevent bleeding or bruising.

Timeline: Report available in 7 days after sample receipt.

Patient Instructions

1
Before the Test:No fasting required. Inform your doctor about any medications or health conditions.
2
During the Test:A blood sample will be collected via venipuncture.
3
After the Test:The sample is processed for sequencing analysis. You can resume normal activities.

About This Test

Who Should Get This Test

To detect drug resistance mutations and determine the genotype of hepatitis B virus for personalized treatment planning and effective management of chronic hepatitis B.

How to Prepare

  • Collect 3 mL blood in two Lavender Top (EDTA) tubes.
  • Separate plasma aseptically within 2 hours of collection.
  • Ship samples refrigerated or frozen as per stability guidelines.

Doctor's Notes

Reviewed by — MBBS, MD (Microbiology) · Reg. No. 27670

"This test is essential for managing hepatitis B patients with suspected drug resistance, guiding effective antiviral therapy and improving outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypePlasma
Sample Volume3 mL
ContainerLavender Top (EDTA) tubes
Collection MethodVenipuncture

Sample Stability

Room Temperature: 6 hours
Refrigerator (2-8°C): 72 hours
Frozen (-20°C or below): 6 months
Sample Rejection Criteria:
  • Hemolyzed or insufficient sample volume
  • Improperly labeled or contaminated samples
  • Samples not stored according to stability conditions

Understanding Your Results

Results indicate the presence or absence of specific drug resistance mutations and identify the hepatitis B virus genotype, guiding treatment decisions.
📊

Resistance to Lamivudine, Telbivudine, and Entecavir

📊

Often co-occurs with M204V; enhances resistance to Lamivudine

📊

Resistance to Lamivudine, Telbivudine, and Entecavir

📊

Resistance to Adefovir and Telbivudine

📊

Resistance to Adefovir and Tenofovir

📊

Specific genotype may influence disease progression and treatment response

⚠️ When to Consult a Doctor:

If you experience symptoms of hepatitis B, have been diagnosed with HBV, or if drug resistance is detected in your test results.

Limitations

  • Detects only specific mutations listed; may not identify rare resistance variants
  • Genotyping accuracy dependent on viral load

Risks & Considerations

  • Minor pain or bruising at the blood draw site
  • Rare risk of infection or fainting

Interfering Factors

  • Hemolyzed blood samples
  • Improper sample storage or handling
  • Contamination during collection

Frequently Asked Questions

What is the Hepatitis B Viral Drug Resistance & Genotyping Test?
It is a specialized blood test that detects mutations causing drug resistance and identifies the genotype of the hepatitis B virus to guide personalized treatment.
Why is this test important for hepatitis B patients?
It helps determine if the virus is resistant to antiviral drugs, allowing doctors to choose effective therapies and avoid treatment failure.
How is the test performed?
A blood sample is collected in EDTA tubes, plasma is separated, and sequencing technology analyzes specific mutations and genotypes.
What samples are required for the test?
3 mL of plasma from two Lavender Top (EDTA) tubes, with plasma separated within 2 hours of collection.
Is fasting required before the test?
No, no special preparation or fasting is required.
How long does it take to get results?
Results are typically available within 7 days after sample receipt.
What do the results indicate?
Results show if drug resistance mutations are present and identify the HBV genotype, informing treatment plans.
What mutations does this test detect?
It detects M204I, L180M, M204V, A181 T/V, and N236T mutations linked to resistance against Lamivudine, Telbivudine, Entecavir, Adefovir, and Tenofovir.
How much does the test cost?
The test costs INR 13,000 at DNA Labs India, with free home sample collection available.
Is home collection available for this test?
Yes, DNA Labs India offers free home collection for online bookings across India.
What is the turnaround time for reports?
Reports are delivered within 7 days via online portal, email, or WhatsApp.
Who should consider taking this test?
Individuals diagnosed with chronic hepatitis B, on antiviral therapy with poor response, or experiencing symptoms like jaundice or fatigue.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.