Hepatitis B Virus Genotyping Drug Resistance & Quantitative PCR Test
Hepatitis B Virus Genotyping Drug Resistance & Quantitative PCR Test test available at DNA Labs India for ₹18,135. Uses Sequencing, Real Time PCR on Plasma from EDTA tubes samples. Results in Reports are available within 7 days of sample collection.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Pasupathy Arumugam
Consultant Pathologist · Reg: 21521
Last reviewed: September 7, 2026
Overview
The purpose of this test is to detect hepatitis B virus genotypes, identify drug resistance mutations, and quantify viral DNA levels. It assists in diagnosing HBV infection, guiding antiviral therapy selection, monitoring treatment efficacy, and assessing the risk of disease complications such as liver damage or cancer. The test is essential for personalized medicine in hepatitis B management.
- Test Code
- 716
- Price
- ₹18,135
- Sample Type
- Plasma from EDTA tubes
- Result Time
- Reports are available within 7 days of sample collection.
- Fasting Required
- Yes (12 hours)
- Method
- Sequencing, Real Time PCR
Sample Collection
12 hours fasting is recommended. Inform the doctor about any medications or supplements being taken.
Method: Venipuncture
Laboratory Analysis
Standard blood draw procedure. Plasma will be separated aseptically from EDTA tubes.
Report Delivery
Apply pressure to the puncture site. Resume normal activities; avoid strenuous exercise for a few hours.
Timeline: Reports are available within 7 days of sample collection.
Patient Instructions
About This Test
Who Should Get This Test
The purpose of this test is to detect hepatitis B virus genotypes, identify drug resistance mutations, and quantify viral DNA levels. It assists in diagnosing HBV infection, guiding antiviral therapy selection, monitoring treatment efficacy, and assessing the risk of disease complications such as liver damage or cancer. The test is essential for personalized medicine in hepatitis B management.
How to Prepare
- Collect 3 mL (2 mL min.) blood in 2 Lavender Top (EDTA) tubes.
- Separate plasma aseptically within 2 hours of collection.
- Ship samples refrigerated or frozen as per stability guidelines.
- Maintain sample integrity during transport.
Doctor's Notes
Reviewed by Dr Pasupathy Arumugam — MBBS, MD (Pathology) · Reg. No. 21521
"This test is crucial for identifying HBV drug resistance and viral load, guiding antiviral therapy adjustments to prevent complications like liver cirrhosis and hepatocellular carcinoma."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Samples received without proper labeling
- Insufficient sample volume
- Specimen not processed as per instructions (e.g., delayed separation)
- Contaminated or hemolyzed samples
Understanding Your Results
HBV Genotype Identified
Indicates the specific strain of HBV, which may influence disease progression and treatment response.
Drug Resistance Mutations Detected
Suggests resistance to specific antiviral drugs, guiding therapy adjustments to avoid treatment failure.
Viral Load High (e.g., > 2000 IU/mL)
Indicates active viral replication; may require antiviral therapy initiation or modification.
Viral Load Low or Undetectable
Suggests effective viral suppression; continue monitoring as per clinical guidelines.
Consult a doctor if you experience symptoms of hepatitis B (e.g., jaundice, fatigue, abdominal pain), if test results indicate drug resistance or high viral load, or for personalized treatment planning based on genotyping results.
Limitations
- ⚠May not detect all rare HBV mutations
- ⚠Quantitative PCR limits of detection vary by lab
- ⚠Results should be interpreted in clinical context
- ⚠Not a standalone diagnostic for hepatitis B; requires correlation with other tests
Risks & Considerations
- ●Minor bruising or pain at the puncture site
- ●Rare risk of infection or dizziness
Interfering Factors
- ●Hemolyzed or lipemic samples
- ●Improper sample storage or handling
- ●Contamination during collection
- ●Use of certain anticoagulants other than EDTA
Frequently Asked Questions
What is the Hepatitis B Virus Genotyping Drug Resistance & Quantitative PCR Test?
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Is home sample collection available?
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Can this test diagnose hepatitis B?
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