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HLA Hypersensitivity to Carbamazepine & Phenytoin (B*15:02) Test Cost

Original price was: ₹12,000.Current price is: ₹8,000.

-33%

Clinical studies have demonstrated association between some HLA genotypes and drug induced adverse skin reactions. Presence of HLA B*15:02 allele increases the risk of developing Toxic Epidermal Necrolysis (TEN) or Stevens- Johnson Syndrome (SJS) which is a milder form of TEN. The frequency of this allele is 10-15% in Chinese, 2-4% in South East Asians including Indians and <1% in Japanese & Koreans. This allele has also been associated with adverse reactions to Lamotrigene used for treating Epilepsy and Bipolar disorder.

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HLA Hypersensitivity to Carbamazepine & Phenytoin (B*15:02) Test Cost INR:8000 Symptoms Diagnosis

HLA hypersensitivity to carbamazepine and phenytoin is a serious drug reaction that can lead to life-threatening conditions. It is important to get tested for this condition if you are taking these medications, or if you have a history of hypersensitivity reactions to drugs. The HLA (human leukocyte antigen) test is a genetic test that can determine your risk for hypersensitivity to these drugs. DNA Labs India offers this test at a cost of INR 8000.

Symptoms of HLA Hypersensitivity to Carbamazepine & Phenytoin

The symptoms of HLA hypersensitivity to carbamazepine and phenytoin can be mild or severe, and can include:

  • Skin rash
  • Fever
  • Swollen lymph nodes
  • Joint pain
  • Nausea and vomiting
  • Shortness of breath
  • Seizures
  • Organ failure

If you experience any of these symptoms while taking carbamazepine or phenytoin, it is important to seek medical attention immediately.

Diagnosis of HLA Hypersensitivity to Carbamazepine & Phenytoin

The HLA test is a genetic test that can determine your risk for hypersensitivity to carbamazepine and phenytoin. The test looks for the presence of the HLA-B*15:02 gene, which has been linked to an increased risk of hypersensitivity to these drugs. If you test positive for the HLA-B*15:02 gene, your doctor may recommend alternative medications to avoid the risk of hypersensitivity.

Cost of HLA Hypersensitivity to Carbamazepine & Phenytoin Test

The cost of the HLA hypersensitivity to carbamazepine and phenytoin test at DNA Labs India is INR 8000. This cost includes the genetic test and the interpretation of the results by a qualified genetic counselor. The test is non-invasive and requires only a small blood or saliva sample.

Conclusion

If you are taking carbamazepine or phenytoin, or if you have a history of hypersensitivity reactions to drugs, it is important to get tested for HLA hypersensitivity to these medications. The HLA test offered by DNA Labs India can determine your risk for hypersensitivity and help you and your doctor make informed decisions about your medication regimen. The cost of the test is INR 8000, and the results can provide peace of mind and potentially life-saving information.

Clinical studies have demonstrated association between some HLA genotypes and drug induced adverse skin reactions. Presence of HLA B*15:02 allele increases the risk of developing Toxic Epidermal Necrolysis (TEN) or Stevens- Johnson Syndrome (SJS) which is a milder form of TEN. The frequency of this allele is 10-15% in Chinese, 2-4% in South East Asians including Indians and <1% in Japanese & Koreans. This allele has also been associated with adverse reactions to Lamotrigene used for treating Epilepsy and Bipolar disorder.

Test NameHLA Hypersensitivity to Carbamazepine & Phenytoin (B*15:02) Test
Sample type4 mL (3 mL min.) whole blood in 1 Lavender Top (EDTA) tube OR 6 mL (3 mL min.) whole blood in 1 Yellow Top (ACD) tube OR Buccal swab collected in a sterile container. Ship refrigerated. DO NOT FREEZE.
Test typeNeurologist, Dermatologist
Pre-test InformationNo special preparation required
DiseaseDisorders of Nervous System, Disorders of Skin
MethodPCR, Sequencing
PurposeNULL
PreparationRoom Temperature: NA, Refrigerator:96 hrs, Frozen: NA
FastingNo special preparation required
Get Reports10-12 days
Test PriceINR ₹ 8000

 Note: We offer free home sample collection for online bookings for HLA Hypersensitivity to Carbamazepine & Phenytoin (B*15:02) Test and the test costs special discounted price of 8000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.