IMMUNOHISTOCHEMISTRY E-CADHERIN (ECAD) Test: Symptoms, Diagnosis, and Cost
Immunohistochemistry (IHC) is a diagnostic tool that helps in the identification of specific proteins in tissues. It is commonly used in the detection of cancerous cells and their characterization. E-cadherin (ECAD) is a protein that plays an essential role in the adhesion of cells, and its loss is associated with the development and progression of cancer. The ECAD test is used to determine the presence of ECAD in tissues and its level of expression.
Symptoms
The ECAD test is commonly used in the diagnosis of cancer. The loss of ECAD is associated with the development and progression of various types of cancer, including breast, gastric, colorectal, and pancreatic cancers. The symptoms of these cancers vary depending on the type and stage of cancer. Some common symptoms include:
- Unexplained weight loss
- Fatigue
- Persistent cough
- Difficulty swallowing
- Bloating or abdominal pain
- Changes in bowel or bladder habits
- Unusual bleeding or discharge
If you experience any of these symptoms, it is essential to consult a doctor for further evaluation and diagnosis.
Diagnosis
The ECAD test is performed on tissue samples obtained from a biopsy or surgery. The tissue sample is fixed in formalin and embedded in paraffin wax. Thin sections of the tissue are cut and placed on glass slides. The slides are then stained with antibodies that specifically bind to ECAD. The presence and level of ECAD expression are determined by examining the stained slides under a microscope.
The ECAD test is commonly used in the diagnosis of cancer. It helps in the identification and characterization of cancer cells and their behavior. The loss of ECAD is associated with the development and progression of cancer and can help in determining the prognosis of the disease.
Cost
The cost of the ECAD test in India varies depending on the laboratory and location. On average, the cost of the ECAD test in India is around INR 3000. However, the cost may vary depending on the laboratory, location, and other factors.
It is essential to consult a doctor before undergoing the ECAD test. The doctor can recommend the appropriate laboratory for the test and provide guidance on the cost and other factors.
Conclusion
The ECAD test is an essential diagnostic tool in the diagnosis of cancer. The loss of ECAD is associated with the development and progression of cancer, and the ECAD test can help in determining the prognosis of the disease. If you experience any symptoms of cancer, it is essential to consult a doctor for further evaluation and diagnosis. The cost of the ECAD test may vary depending on the laboratory and location, and it is essential to consult a doctor for guidance on the appropriate laboratory and cost.
E-Cadherin (ECAD) is typically associated with epithelial differentiation. It is immunoreactive in epithelial neoplasms as well as mesenchymal tumors with epithelial characteristics like Synovial sarcoma. Strong E-cadherin membranous staining is used to define Ductal carcinomas of breast & differentiate from Lobular carcinomas which are negative. Loss of cell surface E-Cadherin expression is also seen in Solid pseudopapillary neoplasms of the pancreas.
| Test Name | Immunohistochemistry E-Cadherin (ECAD) Test |
|---|---|
| Sample type | Submit tumor tissue in 10% Formal-saline OR Formalin fixed paraffin embedded block. Ship at room temperature. Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Test type | Oncologist, Pathologist |
| Pre-test Information | Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Disease | Cancer |
| Method | Immunohistochemistry |
| Purpose | NULL |
| Preparation | Room Temperature: NA, Refrigerator:NA, Frozen: NA |
| Fasting | Provide a copy of the Histopathology report, Site of biopsy and Clinical history. |
| Get Reports | Sample Daily by 6 pm; Report Block: 5 days Tissue Biopsy: 5 days Tissue large complex : 7 days |
| Test Price | INR ₹ 3000 |
Note: We offer free home sample collection for online bookings for Immunohistochemistry E-Cadherin (ECAD) Test and the test costs a special discounted price of 3000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
