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Immunohistochemistry Estrogen Receptor (ER) Test

DNA Labs India | ISO 9001:2015 Certified

Immunohistochemistry Estrogen Receptor (ER) Test

Short Name: Estrogen Receptor IHC Test

Also known as: Estrogen Receptor Immunohistochemistry, ER IHC Test, IHC ER Test

Immunohistochemistry Estrogen Receptor (ER) Test test available at DNA Labs India for ₹1,708. Uses Immunohistochemistry on Tumor Tissue samples. Results in Results typically available within 5-7 working days from sample receipt.. Free home collection in 300+ cities across India.

Diagnostic TestFemaleAdults🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 7, 2026

Overview

To determine the presence of estrogen receptors in breast cancer cells for guiding hormone therapy and assessing prognosis.

Test Code
990
Price
₹1,708
Sample Type
Tumor Tissue
Result Time
Results typically available within 5-7 working days from sample receipt.
Fasting Required
No
Method
Immunohistochemistry
Step 1

Sample Collection

Provide copy of histopathology report, site of biopsy, and clinical history.

Method: Biopsy or Surgery

Step 2

Laboratory Analysis

Tissue sample obtained via biopsy or surgery under medical supervision.

Step 3

Report Delivery

Sample preserved in formalin and transported to the laboratory for analysis.

Timeline: Results typically available within 5-7 working days from sample receipt.

Patient Instructions

1
Before the Test:No specific preparation needed, but ensure all required documentation is provided.
2
During the Test:Laboratory processes the tissue sample using immunohistochemical staining to detect estrogen receptors.
3
After the Test:Results are compiled and reported; follow-up with oncologist recommended.

About This Test

Who Should Get This Test

To determine the presence of estrogen receptors in breast cancer cells for guiding hormone therapy and assessing prognosis.

How to Prepare

  • Submit tumor tissue in 10% formal-saline or formalin fixed paraffin embedded block
  • Ship at room temperature
  • Include a copy of the histopathology report, biopsy site, and clinical history

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"ER status is crucial for determining hormone therapy in breast cancer, influencing treatment decisions and prognosis."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeTumor Tissue
Sample VolumeAs required for analysis
Container10% Formal-saline or Formalin fixed paraffin embedded block
Collection MethodBiopsy or Surgery

Sample Stability

Room temperature: Stable for transport within recommended timeframes
Long-term storage: As per laboratory protocol to preserve tissue integrity
Sample Rejection Criteria:
  • Inadequate tissue sample
  • Improper preservation or fixation
  • Missing clinical information or documentation

Understanding Your Results

Results indicate the presence or absence of estrogen receptors, which is critical for determining eligibility for hormone therapy in breast cancer.
📊

Cancer cells have estrogen receptors, likely to respond to hormone therapy such as tamoxifen.

Status: Positive

📊

Cancer cells lack estrogen receptors, less likely to respond to hormone therapy, and alternative treatments may be considered.

Status: Negative

⚠️ When to Consult a Doctor:

If you have a breast lump, abnormal mammogram, or other symptoms suggestive of breast cancer, consult an oncologist for evaluation and possible biopsy for ER testing.

Limitations

  • ⚠Not for primary diagnosis; requires histopathological confirmation
  • ⚠Results may vary based on tumor heterogeneity and sample quality

Risks & Considerations

  • ●Minimal risks associated with biopsy procedure (e.g., infection, bleeding)
  • ●Standard risks of tissue collection under medical supervision

Interfering Factors

  • ●Tissue fixation time
  • ●Storage conditions
  • ●Technical errors in staining
  • ●Tumor heterogeneity

Compare With Similar Tests

TestImmunohistochemistry Estrogen Receptor (ER) Test
ComparisonImmunohistochemistry Estrogen Receptor (ER) Test

Frequently Asked Questions

What is the Immunohistochemistry Estrogen Receptor (ER) Test?
It is a diagnostic test that detects estrogen receptors in breast cancer cells using immunohistochemical staining on tissue samples.
Why is the ER test important for breast cancer patients?
It helps determine if the cancer is likely to respond to hormone therapy, guiding treatment decisions and improving outcomes.
How is the ER test performed?
The test is performed on a tissue sample from a biopsy or surgery, stained and examined under a microscope for estrogen receptors.
What does a positive ER test result mean?
A positive result indicates that cancer cells have estrogen receptors, making them responsive to hormone therapy like tamoxifen.
What does a negative ER test result mean?
A negative result means cancer cells lack estrogen receptors, so hormone therapy may not be effective, and other treatments are considered.
What is the cost of the ER test at DNA Labs India?
The test costs INR 1708.2, with home collection available at no extra charge in select cities.
How can I book the ER test with home collection?
You can book online through the DNA Labs India website or by contacting their customer service for home sample collection.
What is the turnaround time for ER test results?
Results are typically available within 5-7 working days from the time the sample is received.
Do I need to fast before the ER test?
No fasting is required. Provide necessary documentation like histopathology report and clinical history.
What samples are required for the ER test?
A tumor tissue sample obtained via biopsy or surgery, submitted in 10% formal-saline or formalin fixed paraffin embedded block.
Is the ER test covered by insurance?
Coverage depends on your insurance policy. Check with your provider or contact DNA Labs India for assistance.
Can men undergo the ER test for breast cancer?
Yes, although breast cancer is more common in women, men can also develop it and may benefit from ER testing for treatment planning.
Can the ER test be repeated if cancer recurs?
Yes, the ER test can be repeated on new tissue samples if there is recurrence to reassess receptor status and guide treatment.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

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