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DNA Labs India

KIR (Killer cell immunoglobulin-like receptor) Genotyping Test

DNA Labs India | ISO 9001:2015 Certified

KIR (Killer cell immunoglobulin-like receptor) Genotyping Test

Short Name: KIR Genotyping Test

Also known as: KIR Genotyping, Killer Cell Immunoglobulin-like Receptor Genotyping, KIR Gene Typing

KIR (Killer cell immunoglobulin-like receptor) Genotyping Test test available at DNA Labs India for ₹13,000. Uses Luminex SSO, Illumina MiSeq verification on Whole Blood samples. Results in Samples collected by 9 am are reported within 2 working days.. Free home collection in 300+ cities across India.

Genetic TestAdults🏠 Home Collection

🩺 Medically Reviewed By

Overview

KIR genotyping helps evaluate NK cell receptor gene variants that affect pregnancy maintenance, cancer cell surveillance, viral infection resistance, and bone marrow transplantation success.

Test Code
3508
Price
₹13,000
Sample Type
Whole Blood
Result Time
Samples collected by 9 am are reported within 2 working days.
Fasting Required
No
Method
Luminex SSO, Illumina MiSeq verification
Step 1

Sample Collection

No special preparation or fasting is required.

Method: Venipuncture

Step 2

Laboratory Analysis

A 4 mL whole blood sample is collected in a lavender top EDTA tube or 6 mL in a yellow top ACD tube by venipuncture.

Step 3

Report Delivery

Resume normal activities immediately after sample collection.

Timeline: Samples collected by 9 am are reported within 2 working days.

Patient Instructions

1
Before the Test:No fasting required. Book online for free home sample collection.
2
During the Test:A simple blood draw from the arm is performed by a trained phlebotomist.
3
After the Test:Mild bruising at the puncture site may occur and resolves quickly.

About This Test

Who Should Get This Test

KIR genotyping helps evaluate NK cell receptor gene variants that affect pregnancy maintenance, cancer cell surveillance, viral infection resistance, and bone marrow transplantation success.

How to Prepare

  • Use lavender top EDTA tube or yellow top ACD tube.
  • Collect 4 mL whole blood in EDTA or 6 mL in ACD.
  • Ship refrigerated. Do not freeze.

Doctor's Notes

Reviewed by — MBBS, MD (Medical Genetics) · Reg. No. 8532

"KIR genotyping with HLA-C typing helps assess maternal-fetal immune interactions and transplant donor selection."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeWhole Blood
Sample Volume4 mL (3 mL min.) whole blood in EDTA OR 6 mL (3 mL min.) whole blood in ACD
ContainerLavender Top (EDTA) tube or Yellow Top (ACD) tube
Collection MethodVenipuncture

Sample Stability

Room TemperatureNot applicable
Refrigerator96 hrs
FrozenNot applicable
Sample Rejection Criteria:
  • Frozen sample
  • Volume less than 3 mL
  • Improper sample container

Understanding Your Results

KIR genotyping classifies KIR haplotypes as AA or Bx. The AA haplotype contains predominantly inhibitory KIR genes, while Bx contains additional activating KIR genes. Interpretation should be done with HLA-C typing and clinical context.
📊

AA haplotype with fetal HLA-C2

Associated with increased miscarriage risk

📊

Bx haplotype

Contains activating KIR genes; may influence NK cell activity

📊

Donor KIR Bx with HLA-C1/C2

May enhance graft-versus-leukemia effect after transplant

⚠️ When to Consult a Doctor:

Consult a reproductive specialist, hematologist, or clinical immunologist after receiving the report for interpretation in your clinical context.

Limitations

  • KIR genotyping alone is not diagnostic; clinical correlation is required.
  • HLA-C typing may be needed for reproductive interpretation.
  • Research on KIR genotypes and disease susceptibility is still evolving.

Risks & Considerations

  • Mild bruising at venipuncture site
  • Rare lightheadedness

Interfering Factors

  • Recent blood transfusion
  • Sample freeze-thaw cycle
  • Incorrect anticoagulant tube

Compare With Similar Tests

TestKIR (Killer cell immunoglobulin-like receptor) Genotyping Test
ComparisonKIR (Killer cell immunoglobulin-like receptor) Genotyping Test

Frequently Asked Questions

How does KIR affect pregnancy?
Maternal AA genotype with fetal HLA-C2 increases miscarriage risk 4.7x.
Is any test preparation needed?
No fasting or special preparation is required. A simple blood draw is sufficient.
Is interpretation support available?
Yes, free teleconsultation with the report is provided.
What sample is required for KIR genotyping?
4 mL whole blood in a lavender top EDTA tube or 6 mL whole blood in a yellow top ACD tube. Ship refrigerated.
What is the turnaround time?
Samples collected by 9 am are reported within 2 working days.
How many KIR genes are analyzed?
The test analyzes 16 KIR genes including 2DL1-5, 3DL1-3, 2DS1-5, 2DP1, and 3DP1.
Can KIR genotyping help with IVF failure?
Yes, it may be considered to investigate failed IVF attempts when immune factors are suspected.
Does KIR testing require HLA-C typing of partner or donor?
KIR genotyping is often performed alongside HLA-C testing to assess the interaction between maternal KIR receptors and fetal HLA-C molecules.
In which cities is KIR genotyping available?
DNA Labs India provides this test in 200+ cities including Mumbai, Delhi, Bengaluru, Hyderabad, Chennai, Kolkata, Pune, Ahmedabad, and many more.
What methodology is used?
The test uses Luminex SSO with Illumina MiSeq verification.
What is the cost of KIR genotyping test?
The test is available at a discounted price of Rs 13,000 across India.
Can KIR genotyping be done during pregnancy?
Yes, the test can be done during pregnancy after consulting a doctor.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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