LAMC1 Gene and Pelvic Organ Prolapse: Symptoms, Diagnosis, and NGS Genetic Test Cost
Pelvic organ prolapse (POP) is a common condition among women, especially those who have given birth. It occurs when the muscles and tissues supporting the pelvic organs weaken and stretch, causing the organs to sag or bulge into the vaginal wall. POP can cause discomfort, pain, and embarrassment, affecting a woman’s quality of life.
Recent studies have shown that genetics play a significant role in the development of POP. One gene that has been linked to the condition is LAMC1.
The LAMC1 Gene and Pelvic Organ Prolapse
LAMC1 is a gene that provides instructions for making a protein called laminin-332. This protein is found in the extracellular matrix, which is the network of proteins and other molecules that surrounds cells.
Laminin-332 is crucial for maintaining the integrity of the extracellular matrix and providing structural support to tissues, including the pelvic organs. Studies have shown that mutations in the LAMC1 gene can lead to a weakened extracellular matrix, which can contribute to the development of POP.
Symptoms of Pelvic Organ Prolapse
Some common symptoms of pelvic organ prolapse include:
- A feeling of heaviness or pressure in the pelvic area
- A bulge or lump in the vagina or protruding from the vagina
- Pain or discomfort during sex
- Urinary incontinence
- Bowel problems, such as constipation or fecal incontinence
It’s important to note that not all women with POP experience symptoms. Some women may have mild POP that doesn’t cause discomfort or affect their quality of life.
Diagnosis of Pelvic Organ Prolapse
Pelvic organ prolapse can be diagnosed during a physical exam. Your healthcare provider will ask you to lie down and will examine your pelvic area for any signs of bulging or protrusion. They may also ask you to cough or strain to see if the prolapse becomes more pronounced.
In some cases, imaging tests such as an ultrasound or MRI may be used to get a better look at the pelvic organs and surrounding tissues.
LAMC1-Related NGS Genetic Test Cost
NGS (next-generation sequencing) Genetic Testing is a powerful tool that can help identify genetic mutations that may be contributing to pelvic organ prolapse. This type of testing can be particularly useful for women who have a family history of POP or who have developed the condition at a young age.
The cost of an NGS Genetic Test for LAMC1-related pelvic organ prolapse can vary depending on the testing facility and location. In India, the cost of this test is typically around INR 20,000.
Conclusion
Pelvic organ prolapse is a common condition that can cause discomfort, pain, and embarrassment for women. Genetics, including mutations in the LAMC1 gene, can play a significant role in the development of POP. If you are experiencing symptoms of POP or have a family history of the condition, talk to your healthcare provider about the possibility of genetic testing and the cost of an NGS Genetic Test.
At DNA Labs India, we offer a range of genetic testing services, including NGS Genetic Testing for pelvic organ prolapse. Contact us today to learn more about our services and how we can help you.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for LAMC1 Gene Pelvic organ prolapse, LAMC1 related NGS Genetic Test
| Test Name | LAMC1 Gene Pelvic organ prolapse, LAMC1 related NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Pediatrics |
| Pre-test Information | Clinical History of Patient who is going for LAMC1 Gene Pelvic organ prolapse, LAMC1 related NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with LAMC1 Gene Pelvic organ prolapse, LAMC1 related NGS Genetic Test gene LAMC1 |
| Disease | Dysmorphology |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for LAMC1 Gene Pelvic organ prolapse, LAMC1 related NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with LAMC1 Gene Pelvic organ prolapse, LAMC1 related NGS Genetic Test gene LAMC1 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for LAMC1 Gene Pelvic organ prolapse, LAMC1 related NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
