Understanding the LHB Gene and Hypogonadotropic Hypogonadism: NGS Genetic Test

Hypogonadotropic hypogonadism is a condition that affects the reproductive system. It is a type of secondary hypogonadism, which means that the problem lies not in the testes or ovaries, but in the hypothalamus or pituitary gland. This condition is caused by genetic mutations in various genes, one of which is the LHB gene. In this blog, we will discuss what the LHB gene is, how it is related to hypogonadotropic hypogonadism, and how NGS Genetic Testing can help diagnose this condition.

The LHB Gene

The LHB gene is located on chromosome 19 and encodes for the beta subunit of luteinizing hormone (LH). LH is a hormone that stimulates the production of testosterone in males and estrogen in females. The beta subunit of LH is essential for the proper functioning of the hormone. Mutations in the LHB gene can lead to reduced or absent LH production, which can cause hypogonadotropic hypogonadism.

Hypogonadotropic Hypogonadism

Hypogonadotropic hypogonadism is a condition characterized by low levels of sex hormones (testosterone in males and estrogen in females) due to a problem with the hypothalamus or pituitary gland. This can result in delayed puberty, infertility, and other symptoms such as decreased libido, erectile dysfunction, and hot flashes. There are various genetic mutations that can lead to hypogonadotropic hypogonadism, including mutations in the LHB gene.

NGS Genetic Test

Next-generation sequencing (NGS) Genetic Testing is a powerful tool for diagnosing genetic conditions such as hypogonadotropic hypogonadism. This test involves sequencing the entire genome or specific genes of interest to identify any genetic mutations. NGS Genetic Testing can detect mutations in the LHB gene that may be causing hypogonadotropic hypogonadism.

Symptoms and Diagnosis

The symptoms of hypogonadotropic hypogonadism can vary depending on the severity of the condition and the age of onset. In males, symptoms can include delayed puberty, small testes, decreased muscle mass, and infertility. In females, symptoms can include delayed puberty, absent or irregular menstrual periods, and infertility.

Diagnosis of hypogonadotropic hypogonadism involves a thorough medical history, physical examination, and blood tests to measure hormone levels. Genetic testing, such as NGS Genetic Testing, can also be used to identify any genetic mutations that may be causing the condition.

Cost of NGS Genetic Test

The cost of NGS Genetic Testing for hypogonadotropic hypogonadism can vary depending on the laboratory and the specific genes being sequenced. However, on average, the cost of this test in India is around INR 20,000.

Conclusion

The LHB gene plays an important role in the production of luteinizing hormone, which is essential for the proper functioning of the reproductive system. Mutations in this gene can lead to hypogonadotropic hypogonadism, a condition characterized by low levels of sex hormones. NGS Genetic Testing can be used to diagnose this condition by identifying any genetic mutations that may be causing it. If you are experiencing symptoms of hypogonadotropic hypogonadism, it is important to consult with a healthcare professional who can help diagnose and treat the condition.

At DNA Labs India, we offer NGS Genetic Testing for hypogonadotropic hypogonadism and other genetic conditions. Contact us today to learn more.

 Note: We offer free home sample collection for online bookings for LHB Gene Hypogonadotropic hypogonadism NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.