Precocious Puberty in Males: Understanding LHCGR Gene and NGS Genetic Test
Introduction
Precocious puberty is a condition that affects boys and girls, but it is more common in girls. It refers to the onset of puberty before the age of 8 in girls and 9 in boys. Precocious puberty in males is a rare condition, but it can have serious consequences if left untreated. One of the genes associated with precocious puberty in males is the LHCGR gene. In this blog, we will discuss the LHCGR gene, precocious puberty in males, symptoms, diagnosis, and the NGS Genetic Test cost in India.
The LHCGR Gene
The LHCGR gene is located on chromosome 2 and encodes the luteinizing hormone/choriogonadotropin receptor (LHCGR). This receptor is found on the surface of Leydig cells in the testes and plays a critical role in the production of testosterone. Mutations in the LHCGR gene can lead to precocious puberty in males.
Precocious Puberty in Males
Precocious puberty in males is defined as the onset of puberty before the age of 9. It is a rare condition, affecting only 1 in 5,000 to 10,000 boys. The condition is caused by an increase in testosterone production, which leads to the development of secondary sexual characteristics such as pubic hair, facial hair, and deepening of the voice. Precocious puberty in males can have serious consequences such as reduced final height, infertility, and psychological issues.
Symptoms of Precocious Puberty in Males
The symptoms of precocious puberty in males include:
- Growth of pubic and facial hair
- Enlargement of the testicles
- Deepening of the voice
- Acne
- Body odor
- Early growth spurt
Diagnosis of Precocious Puberty in Males
The diagnosis of precocious puberty in males involves a physical exam, blood tests, and imaging tests. Blood tests can measure the levels of testosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH). Imaging tests such as MRI can also be used to visualize the pituitary gland and rule out any tumors.
NGS Genetic Test
The NGS Genetic Test is a type of genetic test that can identify mutations in the LHCGR gene. This test uses next-generation sequencing technology to analyze the DNA sequence of the gene and detect any mutations. The test can be performed on a blood sample and is a non-invasive procedure. The NGS Genetic Test cost in India is approximately INR 20,000.
Conclusion
Precocious puberty in males is a rare condition that can have serious consequences if left untreated. The LHCGR gene is one of the genes associated with precocious puberty in males. Symptoms of the condition include the growth of pubic and facial hair, enlargement of the testicles, and deepening of the voice. Diagnosis involves a physical exam, blood tests, and imaging tests. The NGS Genetic Test can be used to identify mutations in the LHCGR gene and is a non-invasive procedure that costs approximately INR 20,000 in India. Early diagnosis and treatment of precocious puberty in males can prevent long-term complications and improve outcomes.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for LHCGR Gene Precocious puberty, male NGS Genetic Test
| Test Name | LHCGR Gene Precocious puberty, male NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | General Physician |
| Pre-test Information | Clinical History of Patient who is going for LHCGR Gene Precocious puberty, male NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with LHCGR Gene Precocious puberty, male NGS Genetic Test gene LHCGR |
| Disease | Hepatology Nephrology Endocrinology Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for LHCGR Gene Precocious puberty, male NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with LHCGR Gene Precocious puberty, male NGS Genetic Test gene LHCGR |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for LHCGR Gene Precocious puberty, male NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
