LIG4 Gene and LIG4 Syndrome: Symptoms, Diagnosis, and NGS Genetic Test Cost in India
LIG4 syndrome, also known as DNA ligase IV syndrome, is a rare genetic disorder caused by mutations in the LIG4 gene. This gene is responsible for encoding the DNA ligase IV enzyme, which is essential for repairing damaged DNA. Individuals with LIG4 syndrome have a defective DNA repair mechanism, which leads to various health problems.
Symptoms of LIG4 Syndrome
The symptoms of LIG4 syndrome can vary widely, depending on the severity of the condition and the specific mutations present in the LIG4 gene. Some common symptoms of LIG4 syndrome include:
- Increased susceptibility to infections
- Growth delays and developmental delays
- Increased risk of cancer, especially leukemia and lymphoma
- Abnormal facial features, such as a small head size and a prominent forehead
- Low birth weight and small body size
- Intellectual disability or learning difficulties
Diagnosis of LIG4 Syndrome
LIG4 syndrome is diagnosed through genetic testing, which can identify mutations in the LIG4 gene. This testing can be done using a variety of methods, including:
- Next-generation sequencing (NGS)
- Sanger sequencing
- PCR-based assays
NGS is a particularly useful method for diagnosing LIG4 syndrome, as it can simultaneously test for multiple genes and mutations at once. This makes it a faster and more efficient method than other types of genetic testing.
NGS Genetic Test Cost in India
The cost of an NGS Genetic Test for LIG4 syndrome in India can vary depending on the laboratory and the specific tests ordered. On average, the cost of an NGS Genetic Test for LIG4 syndrome in India is around INR 20,000.
It’s important to note that this is just an estimate, and the actual cost of testing may vary depending on a variety of factors. It’s always a good idea to check with your healthcare provider or the testing laboratory to get an accurate estimate of the cost.
Conclusion
LIG4 syndrome is a rare genetic disorder caused by mutations in the LIG4 gene. Individuals with LIG4 syndrome have a defective DNA repair mechanism, which leads to various health problems. Symptoms of LIG4 syndrome can vary widely, and the condition is diagnosed through genetic testing. Next-generation sequencing (NGS) is a particularly useful method for diagnosing LIG4 syndrome, and the cost of an NGS Genetic Test in India is around INR 20,000.
If you suspect that you or a loved one may have LIG4 syndrome, it’s important to seek medical attention and discuss genetic testing options with your healthcare provider.
At DNA Labs India, we offer a variety of genetic testing services, including NGS Genetic Testing for LIG4 syndrome. Our team of experts is dedicated to providing accurate and reliable testing services to help individuals and families make informed healthcare decisions. Contact us today to learn more.
| Test Name | LIG4 Gene LIG4 syndrome NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Dermatologist |
| Pre-test Information | Clinical History of Patient who is going for LIG4 Gene LIG4 syndrome NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with LIG4 Gene LIG4 syndrome NGS Genetic Test gene LIG4 |
| Disease | Osteology Dermatology Immunology Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for LIG4 Gene LIG4 syndrome NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with LIG4 Gene LIG4 syndrome NGS Genetic Test gene LIG4 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for LIG4 Gene LIG4 syndrome NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
