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Liver Kidney Microsomal (LKM) Antibody IFA Test

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Liver Kidney Microsomal (LKM) Antibody IFA Test

Short Name: LKM Antibody IFA Test

Also known as: LKM Antibody Test, Anti-LKM Antibody Test, Liver Kidney Microsomal Antibody Test

Liver Kidney Microsomal (LKM) Antibody IFA Test test available at DNA Labs India for ₹1,872. Uses Immunofluorescence Assay (IFA) on Serum samples. Results in Same day. Free home collection in 300+ cities across India.

Immunofluorescence Assay (IFA)🏠 Home Collection

Overview

The primary purpose of the Liver Kidney Microsomal (LKM) Antibody IFA Test is to detect the presence of LKM antibodies, which are autoantibodies associated with autoimmune hepatitis type 2. This test aids in confirming the diagnosis of autoimmune hepatitis, differentiating it from other liver diseases, and guiding appropriate treatment strategies.

Test Code
1181
Price
₹1,872
Sample Type
Serum
Result Time
Same day
Fasting Required
No
Method
Immunofluorescence Assay (IFA)
Step 1

Sample Collection

No special preparation required. Inform your doctor about any medications or supplements you are taking.

Method: Venipuncture

Step 2

Laboratory Analysis

A healthcare professional will draw blood from a vein in your arm using a needle. The procedure is quick and typically takes a few minutes.

Step 3

Report Delivery

Apply pressure to the puncture site with a cotton ball to stop bleeding. You may experience minor bruising or discomfort, which usually resolves quickly.

Timeline: Same day

Patient Instructions

1
Before the Test:No fasting or special preparation required. Inform your healthcare provider about any medications.
2
During the Test:A blood sample will be drawn from your arm vein. The process is quick and minimally invasive.
3
After the Test:You can resume normal activities immediately. Apply pressure to the puncture site to prevent bruising.

About This Test

Who Should Get This Test

The primary purpose of the Liver Kidney Microsomal (LKM) Antibody IFA Test is to detect the presence of LKM antibodies, which are autoantibodies associated with autoimmune hepatitis type 2. This test aids in confirming the diagnosis of autoimmune hepatitis, differentiating it from other liver diseases, and guiding appropriate treatment strategies.

How to Prepare

  • Collect 2 mL (minimum 1 mL) of serum from one SST (Serum Separator Tube)
  • Ship samples refrigerated (2-8°C) or frozen (-20°C) to maintain stability
  • Label the sample correctly with patient details and test name

Doctor's Notes

"LKM antibody testing is crucial for diagnosing autoimmune hepatitis, a condition that requires early intervention to prevent liver damage. If you have symptoms like jaundice or fatigue, consult a gastroenterologist for evaluation."

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature6 hours
Refrigerator (2-8°C)1 week
Frozen (-20°C)4 weeks
Sample Rejection Criteria:
  • Sample hemolyzed or insufficient volume
  • Improper labeling or missing patient information
  • Sample stored incorrectly beyond stability limits

Understanding Your Results

Interpretation of LKM Antibody IFA Test results requires clinical context. A positive result indicates the presence of LKM antibodies, which is strongly associated with autoimmune hepatitis type 2. However, it must be correlated with symptoms, liver function tests, and possibly liver biopsy for definitive diagnosis.
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Negative

LKM antibodies not detected; autoimmune hepatitis type 2 is unlikely. Consider other causes of liver disease.

📊

Positive (Elevated)

LKM antibodies detected; suggestive of autoimmune hepatitis type 2. Further evaluation with liver biopsy and clinical assessment recommended.

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Borderline

Results near the cutoff value; repeat testing or additional tests may be needed for confirmation.

⚠️ When to Consult a Doctor:

Consult a doctor if you experience symptoms of liver disease (e.g., jaundice, fatigue, abdominal pain), have abnormal liver function tests, or if your LKM Antibody test results are positive or borderline.

Limitations

  • This test alone may not confirm autoimmune hepatitis; clinical correlation and additional tests are needed
  • False positives can occur in other liver conditions or autoimmune diseases
  • Results should be interpreted by a qualified healthcare professional

Risks & Considerations

  • Minor pain or bruising at the blood draw site
  • Rare risk of infection or dizziness

Interfering Factors

  • Hemolyzed or lipemic samples may affect test accuracy
  • Recent immunosuppressive therapy could reduce antibody levels
  • Cross-reactivity with other autoimmune antibodies possible

Frequently Asked Questions

What is the Liver Kidney Microsomal (LKM) Antibody IFA Test?
It is a blood test that detects LKM antibodies, which are associated with autoimmune hepatitis type 2, an autoimmune liver disease.
Why is the LKM Antibody IFA Test done?
This test is performed to diagnose autoimmune hepatitis, especially when symptoms like jaundice, fatigue, or abnormal liver function tests are present.
How should I prepare for the LKM Antibody IFA Test?
No special preparation is required. You can eat and drink normally before the test unless instructed otherwise by your doctor.
What does a positive LKM Antibody result mean?
A positive result indicates the presence of LKM antibodies, suggesting autoimmune hepatitis type 2. Further tests may be needed for confirmation.
Is the LKM Antibody IFA Test painful?
The test involves a standard blood draw, which may cause minor discomfort or bruising, but it is generally quick and tolerable.
How long does it take to get the results?
Results are typically available on the same day if the sample is received by 9 am.
Can I get the LKM Antibody test done at home?
Yes, DNA Labs India offers free home sample collection for this test across many cities in India.
What is the cost of the LKM Antibody IFA Test in India?
The cost is INR 1872, which includes home collection and report delivery.
Are there any risks associated with the test?
Risks are minimal, including minor bruising or dizziness at the blood draw site. Serious complications are rare.
What other tests might be done along with the LKM Antibody test?
Doctors may order ANA, ASMA, liver function tests, or hepatitis B/C tests to comprehensively evaluate liver health.
How accurate is the LKM Antibody IFA Test?
The test is highly accurate using immunofluorescence assay, but results should be interpreted alongside clinical findings and other tests.
What should I do if my LKM Antibody test is positive?
Consult a gastroenterologist or hepatologist immediately for further evaluation, including possible liver biopsy, and discuss treatment options.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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