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Mitochondrial Antibody (AMA) IFA Test

DNA Labs India | ISO 9001:2015 Certified

Mitochondrial Antibody (AMA) IFA Test

Short Name: AMA IFA Test

Also known as: Mitochondrial Antibody Test, AMA Test, Anti-Mitochondrial Antibody Test

Mitochondrial Antibody (AMA) IFA Test test available at DNA Labs India for ₹1,989. Uses Immunofluorescence Assay (IFA) on Serum samples. Results in Same day report available, depending on sample receipt and processing.. Free home collection in 300+ cities across India.

Immunofluorescence Assay (IFA)Adults🏠 Home Collection

🩺 Medically Reviewed By

Overview

To detect anti-mitochondrial antibodies in serum for the diagnosis of Primary Biliary Cholangitis and Autoimmune Hepatitis, aiding in early intervention and management of autoimmune liver diseases.

Test Code
1247
Price
₹1,989
Sample Type
Serum
Result Time
Same day report available, depending on sample receipt and processing.
Fasting Required
Yes (12 hours)
Method
Immunofluorescence Assay (IFA)
Step 1

Sample Collection

Overnight fasting is preferred. Inform your doctor about any medications or supplements.

Method: Venipuncture

Step 2

Laboratory Analysis

A blood sample will be drawn from a vein in your arm using standard venipuncture procedure.

Step 3

Report Delivery

Apply pressure to the puncture site to prevent bruising. You may resume normal activities.

Timeline: Same day report available, depending on sample receipt and processing.

Patient Instructions

1
Before the Test:Inform your doctor about any medications or supplements you are taking. Fast overnight before sample collection.
2
During the Test:A blood sample will be drawn from a vein in your arm. The procedure is quick and typically takes a few minutes.
3
After the Test:You may experience minor bruising or soreness at the puncture site. Apply pressure as advised.

About This Test

Who Should Get This Test

To detect anti-mitochondrial antibodies in serum for the diagnosis of Primary Biliary Cholangitis and Autoimmune Hepatitis, aiding in early intervention and management of autoimmune liver diseases.

How to Prepare

  • Collect 2 mL serum in SST tube.
  • Ship refrigerated or frozen.
  • Patient should fast overnight before sample collection.

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"The AMA IFA test is crucial for early diagnosis of autoimmune liver diseases, enabling timely treatment to prevent liver damage and improve patient outcomes."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature6 hours
Refrigerator1 week
Frozen2 weeks
Sample Rejection Criteria:
  • Hemolyzed sample
  • Insufficient sample volume
  • Improper container type
  • Mislabeled or unlabeled sample

Understanding Your Results

Results are reported as positive or negative for anti-mitochondrial antibodies. A positive result indicates presence of AMA, associated with autoimmune liver diseases, while a negative result may suggest absence but does not rule out other conditions.
📊

Positive

Presence of AMA, suggestive of Primary Biliary Cholangitis or other autoimmune liver diseases. Clinical correlation is recommended for diagnosis.

📊

Negative

No detectable AMA. Does not rule out other liver conditions; further testing may be needed based on clinical symptoms.

⚠️ When to Consult a Doctor:

If you experience symptoms such as jaundice, fatigue, abdominal pain, or dark urine, consult a gastroenterologist or immunologist for evaluation and potential testing.

Limitations

  • Not useful for indicating the prognosis of the disease or monitoring the course of the disease
  • May yield false positives in other autoimmune conditions
  • Requires clinical correlation and confirmation with other tests
  • Does not replace liver biopsy for definitive diagnosis

Risks & Considerations

  • Bruising at puncture site
  • Infection (rare)
  • Fainting or dizziness
  • Minor discomfort

Interfering Factors

  • Hemolysis
  • Lipemia
  • Recent blood transfusion
  • Interfering substances in serum

Compare With Similar Tests

TestMitochondrial Antibody (AMA) IFA TestLiver Function Tests (LFTs)Immunoglobulin TestsLiver BiopsyAnti-Smooth Muscle Antibody Test
ComparisonMitochondrial Antibody (AMA) IFA TestAssesses liver enzyme levels but does not detect specific antibodies like AMA.Measures immune globulins, which may be elevated in autoimmune diseases but not specific to mitochondria.Invasive test for direct liver tissue examination, considered the gold standard for diagnosis.Detects antibodies associated with autoimmune hepatitis, complementary to AMA testing.

Frequently Asked Questions

What is the Mitochondrial Antibody (AMA) IFA Test?
The AMA IFA Test is a blood test that detects autoantibodies against mitochondria, used to diagnose autoimmune liver diseases like Primary Biliary Cholangitis (PBC) and Autoimmune Hepatitis (AIH).
Why is the AMA IFA Test performed?
It is performed to diagnose autoimmune liver diseases when symptoms such as jaundice, fatigue, or abnormal liver enzymes are present, helping in early intervention.
What does a positive AMA test result mean?
A positive result indicates the presence of anti-mitochondrial antibodies, which are commonly associated with PBC or AIH. Clinical correlation is needed for diagnosis.
How should I prepare for the AMA IFA Test?
Overnight fasting is preferred. Inform your doctor about any medications or health conditions before the test.
What is the cost of the AMA IFA Test in India?
The cost is INR 1989 at DNA Labs India, with home collection available across numerous cities.
Is home sample collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings at the discounted price of INR 1989.
How long does it take to get the test results?
Results are typically available the same day, depending on sample receipt and laboratory processing.
What are the symptoms that may require this test?
Symptoms include fatigue, abdominal pain, jaundice, itching, dark urine, pale stools, loss of appetite, nausea, and weight loss.
Are there any risks associated with the AMA IFA Test?
Risks are minimal and include bruising at the puncture site, infection (rare), or fainting. It is a safe blood draw procedure.
What other tests are used to diagnose autoimmune liver diseases?
Other tests include Liver Function Tests (LFTs), Immunoglobulin Tests, Liver Biopsy, and Anti-Smooth Muscle Antibody Test.
Can the AMA IFA Test be used to monitor treatment?
No, this test is not useful for monitoring the course of the disease or indicating prognosis. It is primarily for diagnosis.
What should I do if my test results are abnormal?
Consult a gastroenterologist or immunologist for further evaluation and to discuss appropriate treatment options based on your clinical situation.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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