Mixing Studies - APTT with Prothrombin Time Studies Test
Short Name: Mixing Studies APTT PT
Also known as: APTT Mixing Study, Prothrombin Time Mixing Study, Coagulation Mixing Studies
Mixing Studies - APTT with Prothrombin Time Studies Test test available at DNA Labs India for ₹3,510. Uses Photo-optical Clot Detection, Clotting Time Analysis on Whole Blood samples. Results in Results are usually available within 1-2 days after sample receipt at the lab.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr SHAILAJA RAGHUNATH MURDESHWAR
Consultant Physician · Reg: 8052
Last reviewed: September 7, 2026
Overview
To diagnose and differentiate between clotting factor deficiencies and inhibitors in patients with abnormal bleeding or clotting tendencies, aiding in the management of coagulation disorders.
- Test Code
- 1251
- Price
- ₹3,510
- Sample Type
- Whole Blood
- Result Time
- Results are usually available within 1-2 days after sample receipt at the lab.
- Fasting Required
- Yes
- Method
- Photo-optical Clot Detection, Clotting Time Analysis
Sample Collection
Overnight fasting is preferred. Discontinue Heparin for 1 day and Oral Anticoagulants for 7 days prior to sampling with physician consent. Duly filled Coagulation Requisition Form (Form 15) is mandatory.
Method: Venipuncture
Laboratory Analysis
Standard venipuncture procedure; sample collected into specified tubes.
Report Delivery
Apply pressure to the puncture site to stop bleeding; keep the area clean and dry.
Timeline: Results are usually available within 1-2 days after sample receipt at the lab.
Patient Instructions
About This Test
Who Should Get This Test
To diagnose and differentiate between clotting factor deficiencies and inhibitors in patients with abnormal bleeding or clotting tendencies, aiding in the management of coagulation disorders.
How to Prepare
- Collect 6 mL whole blood in 2 Blue Top (Sodium Citrate) tubes.
- Mix thoroughly by inversion.
- Transport to lab within 4 hours.
- If delayed, prepare Platelet-Poor Plasma (PPP) within 1 hour: Centrifuge at 3600 rpm for 15 min, transfer supernatant, centrifuge again, and freeze immediately.
- Ship frozen; do not thaw.
Doctor's Notes
Reviewed by Dr SHAILAJA RAGHUNATH MURDESHWAR — MBBS, MD (General Medicine) · Reg. No. 8052
"Early diagnosis through mixing studies can prevent serious complications from clotting disorders and guide appropriate treatment."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed sample
- Incorrect tube type
- Insufficient volume
- Unfilled requisition form
Understanding Your Results
Correction after mixing
Suggests clotting factor deficiency
No correction after mixing
Suggests presence of an inhibitor (e.g., lupus anticoagulant or factor inhibitor)
If you experience symptoms of abnormal bleeding, excessive bruising, or history of clotting disorders, consult a healthcare provider for evaluation and possible testing.
Limitations
- ⚠Test may not detect all types of inhibitors; correlation with clinical history is essential.
- ⚠Results should be interpreted by a qualified healthcare professional.
Risks & Considerations
- ●Minor bruising at the puncture site
- ●Rare risk of infection
- ●Slight dizziness in some individuals
Interfering Factors
- ●Heparin therapy
- ●Oral anticoagulant medications
- ●Sample handling delays
- ●Lipemic or hemolyzed samples
Compare With Similar Tests
| Test | Mixing Studies - APTT with Prothrombin Time Studies Test | Standard APTT Test | Prothrombin Time Test |
|---|---|---|---|
| Comparison | Mixing Studies - APTT with Prothrombin Time Studies Test |
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