MT-TL1 Gene and MELAS Syndrome: Symptoms, Diagnosis and Genetic Testing Cost in India
MT-TL1 gene is a mitochondrial gene that is responsible for the production of a protein called tRNA. This protein is involved in the production of energy in the cells. MT-TL1 gene mutations are associated with several mitochondrial disorders, including MELAS syndrome.
What is MELAS Syndrome?
MELAS (Mitochondrial Encephalomyopathy, Lactic Acidosis, and Stroke-like episodes) syndrome is a rare mitochondrial disorder that affects multiple body systems, including the brain, muscles, and heart. It is caused by mutations in the MT-TL1 gene, which leads to the dysfunction of the mitochondria and the production of energy in the cells.
The symptoms of MELAS syndrome can vary widely, but some common ones include:
- Stroke-like episodes
- Seizures
- Muscle weakness and wasting
- Visual and hearing problems
- Difficulty swallowing
- Heart abnormalities
Diagnosing MELAS Syndrome
Diagnosing MELAS syndrome can be challenging because the symptoms can be similar to those of other conditions. However, there are some diagnostic tests that can help confirm a diagnosis, including:
- Genetic testing: This involves testing for mutations in the MT-TL1 gene.
- Blood and urine tests: These tests can help identify abnormalities in the body’s chemistry that are associated with MELAS syndrome.
- Brain imaging: Imaging tests such as MRI can help identify changes in the brain that are associated with MELAS syndrome.
MT-TL1 Related NGS Genetic Test Cost in India
In India, the cost of MT-TL1 related NGS Genetic Test can vary depending on the laboratory and the location. However, on average, the cost of this test is around INR 20,000.
Conclusion
MT-TL1 gene mutations can lead to several mitochondrial disorders, including MELAS syndrome. Diagnosing this condition can be challenging, but genetic testing and other diagnostic tests can help confirm a diagnosis. If you suspect that you or a loved one may have MELAS syndrome, it’s important to talk to a doctor and get a proper diagnosis.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for MT-TL1 Gene MELAS syndrome, MT-TL1 related NGS Genetic Test
| Test Name | MT-TL1 Gene MELAS syndrome, MT-TL1 related NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Cardiologist |
| Pre-test Information | Clinical History of Patient who is going for MT-TL1 Gene MELAS syndrome, MT-TL1 related NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with MT-TL1 Gene MELAS syndrome, MT-TL1 related NGS Genetic Test gene MT-TL1 |
| Disease | Cardiovascular Pneumology Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | NULL |
| Fasting | Clinical History of Patient who is going for MT-TL1 Gene MELAS syndrome, MT-TL1 related NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with MT-TL1 Gene MELAS syndrome, MT-TL1 related NGS Genetic Test gene MT-TL1 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for MT-TL1 Gene MELAS syndrome, MT-TL1 related NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
