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DNA Labs India

Whole Exome Sequencing + RAW DATA WES Test

DNA Labs India | ISO 9001:2015 Certified

Whole Exome Sequencing + RAW DATA WES Test

Short Name: WES

Also known as: WES, Exome Sequencing, Next-Generation Whole Exome Sequencing

Whole Exome Sequencing + RAW DATA WES Test test available at DNA Labs India for ₹24,000. Uses Next-Generation Sequencing (Illumina HiSeq 2500), Agilent SureSelect capture on Whole Blood (EDTA) samples. Results in Reports are delivered within 4 weeks from the date the sample reaches the lab.. Free home collection in 300+ cities across India.

Molecular🏠 Home Collection

✍️ Written By

🩺 Medically Reviewed By

Dr Pasupathy Arumugam

Dr Pasupathy Arumugam

Consultant Pathologist · Reg: 21521

Last reviewed: September 15, 2026

Overview

The primary purpose of Whole Exome Sequencing is to identify the genetic cause of a suspected inherited disorder when the clinical presentation is broad or when targeted gene panels have not yielded a diagnosis. It is also used to assess recurrence risks in families, guide treatment decisions in oncology, and provide insights into conditions like unexplained epilepsy, cardiomyopathy, and neurodegeneration.

Test Code
6261
CPT Code
81415
ICD Code
Z13.71
Price
₹24,000
Sample Type
Whole Blood (EDTA)
Result Time
Reports are delivered within 4 weeks from the date the sample reaches the lab.
Fasting Required
No
Method
Next-Generation Sequencing (Illumina HiSeq 2500), Agilent SureSelect capture
Step 1

Sample Collection

No fasting is required. Inform your doctor about any medications, especially blood thinners like warfarin, before the test. Avoid major blood thinners if possible, but do not stop any medication without medical advice.

Method: Venipuncture

Step 2

Laboratory Analysis

A trained phlebotomist will collect a blood sample from a vein in your arm. The procedure takes a few minutes and is generally painless.

Step 3

Report Delivery

You can resume normal activities immediately. There are no restrictions after the blood draw. The sample will be transported to the lab following ISO protocols.

Timeline: Reports are delivered within 4 weeks from the date the sample reaches the lab.

Patient Instructions

1
Before the Test:No special preparation is required. However, it is important to provide a detailed clinical history and any prior genetic testing results to aid in interpretation.
2
During the Test:The test involves a simple blood draw. The sample is then sent to the lab for sequencing, which takes several weeks.
3
After the Test:After the test, you will receive a digital report. A genetic counselor will contact you to discuss the results and any recommended follow-up actions.

About This Test

Who Should Get This Test

The primary purpose of Whole Exome Sequencing is to identify the genetic cause of a suspected inherited disorder when the clinical presentation is broad or when targeted gene panels have not yielded a diagnosis. It is also used to assess recurrence risks in families, guide treatment decisions in oncology, and provide insights into conditions like unexplained epilepsy, cardiomyopathy, and neurodegeneration.

How to Prepare

  • No fasting required
  • Avoid blood thinners if possible (consult doctor)
  • Maintain hydration
  • Inform lab of any recent transfusions or transplants

Doctor's Notes

Reviewed by — MBBS, MD (Pathology) · Reg. No. 21521

"Whole exome sequencing is a powerful diagnostic tool for patients with complex or undiagnosed genetic conditions. It provides a comprehensive analysis of protein-coding regions, enabling precise identification of pathogenic variants that may guide clinical management and family counseling."

Last medically reviewed: September 15, 2026

Test Parameters & Specifications

Sample TypeWhole Blood (EDTA)
Sample Volume3-4 mL
ContainerEDTA Vacutainer
Collection MethodVenipuncture

Sample Stability

Room Temperature3 days
Refrigerated (2-8°C)7 days
Frozen (-20°C)1 month
Sample Rejection Criteria:
  • Hemolyzed or clotted sample
  • Incorrect sample volume
  • Sample received after prolonged delay without proper storage
  • Mislabeled or unlabeled sample

Understanding Your Results

The WES report is interpreted by a certified geneticist. Variants are classified based on ACMG guidelines. The report includes primary findings related to the clinical indication and secondary findings that may be medically actionable.
📊

Confirms the genetic diagnosis. Genetic counseling is recommended for family members.

📊

Highly suggestive of disease causality. Further segregation analysis may be needed.

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Insufficient evidence to determine pathogenicity. Additional testing or family studies may be required.

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Does not rule out a genetic cause. Other genetic or non-genetic etiologies should be considered.

⚠️ When to Consult a Doctor:

Consult your referring physician or a genetic counselor if you have questions about your results, if you need help understanding the implications for family members, or if you wish to discuss reproductive options.

Limitations

  • ⚠WES does not detect all types of genetic variants, such as large structural rearrangements, trinucleotide repeat expansions, or deep intronic variants
  • ⚠Mitochondrial DNA variants may not be fully covered
  • ⚠Some regions of the exome may have low coverage, leading to potential false negatives
  • ⚠Variant interpretation may be limited by current medical knowledge
  • ⚠Secondary findings may be identified, requiring careful counseling

Risks & Considerations

  • ●Bruising or discomfort at the needle site
  • ●Rare risk of infection
  • ●Psychological impact of unexpected findings
  • ●Potential for secondary findings unrelated to the original reason for testing

Interfering Factors

  • ●Clotted or hemolyzed blood sample
  • ●Insufficient sample volume
  • ●Recent blood transfusion (within 2 weeks) may dilute patient DNA
  • ●Bone marrow transplantation can lead to mixed DNA profiles
  • ●Contamination during sample collection

Compare With Similar Tests

TestWhole Exome Sequencing + RAW DATA WES TestWhole Exome Sequencing (WES)Targeted Gene Panels
ComparisonWhole Exome Sequencing + RAW DATA WES Test

Frequently Asked Questions

Is fasting required for Whole Exome Sequencing in India?
No, fasting is not required. You can eat and drink normally before the blood draw. The only preparation is to avoid major blood thinners (like warfarin) if possible — please consult your doctor before stopping any medication.
Do you provide help in understanding my genetic test results?
Absolutely. Every WES booking includes free post-test genetic counseling with our certified experts during working hours. We explain primary and secondary findings, inheritance patterns, and implications for family members. Simply email or call us after you receive your report to schedule a telephonic session.
How soon will I receive my ISO?certified digital report?
Your report is delivered within 4 weeks from the date the sample reaches our lab. It will be available as a secure, encrypted PDF via email and on our patient portal. The report includes raw data files and a clinical interpretation signed by a geneticist.
Is there an extra charge for home collection in my city?
No extra charge. The ? 24,000 price already covers home sample collection across 300+ cities. We do not add any hidden fees — you pay only the published price.
How can I book the WES test via WhatsApp or Phone?
You can book 24x7 through our website, or simply send “WES” to +91 98765 43210 on WhatsApp. A care coordinator will respond within minutes to schedule your home collection. You can also call the same number for any queries.
What is the “Room 3 days” preparation mentioned in the test details?
This refers to sample stability — the blood sample should be kept at room temperature (not refrigerated) if it cannot be processed immediately. For you, it simply means you do not need to rush; our phlebotomist will handle transportation following strict ISO protocols.
What does Whole Exome Sequencing cover?
WES covers the protein-coding regions of approximately 23,000 genes, which includes about 180,000 exons. This represents about 1-2% of the genome but contains the majority of known disease-causing variants.
Can WES detect all genetic disorders?
No, WES cannot detect all genetic disorders. It may miss certain types of variants such as large structural rearrangements, trinucleotide repeat expansions, and deep intronic mutations. Some mitochondrial DNA variants may also not be fully covered.
Will I receive raw data files?
Yes, the test includes raw data files (FASTQ/VCF format) which are provided along with the clinical report. These can be used for further analysis or research.
Is genetic counseling included in the price?
Yes, post-test genetic counseling by certified genetic counselors is included in the test price. This service is available during working hours (Mon-Sat, 9 AM – 6 PM) at no extra charge.
What is the difference between WES and Whole Genome Sequencing (WGS)?
WES focuses on the protein-coding regions (exome), while WGS sequences the entire genome, including non-coding regions. WGS is more comprehensive but also more expensive and requires more complex analysis.
How accurate is the WES test?
The test is performed using high-throughput NGS with high coverage depth (?20x for >98% of the exome), ensuring high accuracy. However, no test is 100% sensitive, and results should be interpreted in the context of clinical findings.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

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For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

✓ Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

✓ DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

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