PML RARA t(15;17)(q22;q12) Gene Rearrangement Qualitative PCR Test
Are you experiencing symptoms such as fatigue, frequent infections, and abnormal bleeding or bruising? These symptoms could be indicative of a blood cancer known as acute promyelocytic leukemia (APL). APL is a rare but aggressive form of leukemia that can be caused by a genetic mutation in the PML RARA gene.
The PML RARA t(15;17)(q22;q12) gene rearrangement qualitative PCR test is a diagnostic tool used to detect this genetic mutation. This test is a type of polymerase chain reaction (PCR) test that is highly sensitive and specific, allowing for accurate and reliable detection of the PML RARA gene rearrangement.
Cost of the Test
The cost of the PML RARA t(15;17)(q22;q12) gene rearrangement qualitative PCR test in India is INR 7500. This cost may vary depending on the laboratory where the test is performed and any additional tests that may be required.
Symptoms of APL
APL is a type of acute myeloid leukemia (AML) that is characterized by the abnormal accumulation of immature white blood cells in the bone marrow and blood. Some common symptoms of APL include:
- Fatigue
- Frequent infections
- Abnormal bleeding or bruising
- Shortness of breath
- Fever
- Weight loss
If you are experiencing any of these symptoms, it is important to consult with a healthcare professional for an accurate diagnosis and appropriate treatment.
Diagnosis of APL
The diagnosis of APL typically involves a combination of physical examination, blood tests, and bone marrow biopsy. The PML RARA t(15;17)(q22;q12) gene rearrangement qualitative PCR test is also commonly used to confirm the diagnosis of APL.
If the test results are positive for the PML RARA gene rearrangement, it confirms the diagnosis of APL and helps to determine the appropriate treatment plan. Treatment for APL typically involves a combination of chemotherapy and targeted therapy.
Conclusion
The PML RARA t(15;17)(q22;q12) gene rearrangement qualitative PCR test is an important diagnostic tool for the accurate and reliable detection of the PML RARA gene rearrangement in patients with APL. If you are experiencing symptoms of APL, it is important to consult with a healthcare professional for an accurate diagnosis and appropriate treatment.
At DNA Labs India, we offer a wide range of diagnostic tests, including the PML RARA t(15;17)(q22;q12) gene rearrangement qualitative PCR test, to help healthcare professionals make accurate and timely diagnoses. Contact us today to learn more about our services.
Vast majority of cases of Acute Promyelocytic Leukemia (APL) have a translocation t(15;17)(q22;q12-21) which fuses the Promyelocytic gene (PML) on chromosome band 15q22 to the Retinoic acid receptor alpha (RARA) gene at 17q12-21. This PML / RARA fusion is associated with a good response to all- transretinoic acid therapy.
| Test Name | PML RARA t(1517)(q22q12) Gene Rearrangement Qualitative PCR Test |
|---|---|
| Sample type | 5 mL (3 mL min.) whole blood from 2 Lavender Top (EDTA) tubes. Ship refrigerated. DO NOT FREEZE. Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory. |
| Test type | Oncologist |
| Pre-test Information | Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory. |
| Disease | Leukemia |
| Method | Real Time PCR |
| Purpose | NULL |
| Preparation | Room Temperature: 6 hrs, Refrigerator:72 hrs, Frozen: NA |
| Fasting | Duly filled Genomics Clinical Information Requisition Form (Form 20) is mandatory. |
| Get Reports | Sample Mon / Wed / Fri by 9 am; Report Tue / Thu / Sat |
| Test Price | INR ₹ 7500 |
Note: We offer free home sample collection for online bookings for PML RARA t(1517)(q22q12) Gene Rearrangement Qualitative PCR Test and the test costs a special discounted price of 7500 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
