Prenatal Delta Beta-Thalassaemia Mutation Screening Cost INR:7500 Symptoms Diagnosis
Delta Beta-Thalassaemia is a genetic blood disorder that affects the production of hemoglobin, a protein found in red blood cells that carries oxygen throughout the body. It is caused by mutations in the HBB gene, which provides instructions for making beta-globin, a component of hemoglobin.
Individuals who inherit two copies of the mutated HBB gene, one from each parent, will develop Delta Beta-Thalassaemia major, which is a severe form of the disease. Symptoms typically appear within the first two years of life and include anemia, fatigue, weakness, and jaundice. Without treatment, this condition can lead to life-threatening complications, such as heart failure and severe infections.
On the other hand, individuals who inherit one mutated HBB gene and one normal HBB gene are carriers of Delta Beta-Thalassaemia. They do not usually have any symptoms, but they can pass the mutated gene on to their children.
Diagnosis of Delta Beta-Thalassaemia
Delta Beta-Thalassaemia can be diagnosed through a blood test that measures the amount of hemoglobin in the blood and identifies any abnormal hemoglobin variants. If a person is suspected of having Delta Beta-Thalassaemia, additional tests, such as genetic testing, may be performed to confirm the diagnosis and determine the specific mutation present.
Prenatal Screening for Delta Beta-Thalassaemia
Individuals who are carriers of Delta Beta-Thalassaemia and their partners have a 25% chance of having a child with Delta Beta-Thalassaemia major. Prenatal screening can be done to determine if a developing fetus has the condition.
Prenatal screening involves collecting a sample of the amniotic fluid or placenta and analyzing the DNA for mutations in the HBB gene. This can be done as early as the 10th week of pregnancy. If the fetus is found to have Delta Beta-Thalassaemia major, the parents can decide whether to continue the pregnancy or terminate it.
Cost of Prenatal Delta Beta-Thalassaemia Mutation Screening
The cost of prenatal Delta Beta-Thalassaemia mutation screening in India is approximately INR 7500. This cost may vary depending on the specific testing method used and the laboratory conducting the test.
Conclusion
Delta Beta-Thalassaemia is a genetic blood disorder that can have serious health consequences if left untreated. Prenatal screening can help identify fetuses with Delta Beta-Thalassaemia major, allowing parents to make informed decisions about their pregnancy. The cost of prenatal Delta Beta-Thalassaemia mutation screening in India is relatively affordable, making it accessible to more individuals.
If you suspect that you or your partner may be a carrier of Delta Beta-Thalassaemia, or if you have a family history of the condition, it is important to speak with a healthcare provider about genetic testing and prenatal screening options.
| Test Name | Prenatal Delta Beta-Thalassaemia Mutation Screening |
|---|---|
| Sample type | Amniotic fluid/ Chorionic villi/ Peripheral blood |
| Test type | General Physician |
| Pre-test Information | Prenatal Delta Beta- Thalassaemia mutation screening can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
| Disease | Genetics |
| Method | End Point PCR |
| Purpose | Sterile container/ Sterile Normal Saline Container/ EDTA Vacutainer |
| Preparation | Ambient |
| Fasting | Prenatal Delta Beta- Thalassaemia mutation screening can be done with a Doctor’s prescription. Prescription is not applicable for surgery and pregnancy cases or people planing to travel abroad. |
| Get Reports | 5-6 days |
| Test Price | INR ₹ 7500 |
Note: We offer free home sample collection for online bookings for Prenatal Delta Beta-Thalassaemia Mutation Screening and the test costs a special discounted price of 7500 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
