SH2D1A Gene Lymphoproliferative Syndrome, X-Linked Type 1 NGS Genetic Test: Symptoms, Diagnosis, and Cost

Lymphoproliferative syndrome (LPS) is a group of rare genetic disorders that affect the immune system. LPS is characterized by abnormal growth of lymphocytes, a type of white blood cell, which can lead to various health complications. X-linked lymphoproliferative syndrome type 1 (XLP-1) is a type of LPS that is caused by mutations in the SH2D1A gene. XLP-1 is an X-linked disorder, meaning that it primarily affects males. Females can be carriers of the disorder but are usually asymptomatic.

Symptoms of XLP-1

The symptoms of XLP-1 can vary widely between individuals and can range from mild to severe. Some of the common symptoms of XLP-1 include:

• Recurrent infections
• Enlarged spleen and liver
• Low platelet count (thrombocytopenia)
• Anemia
• Lymphoma
• Hemophagocytic lymphohistiocytosis (HLH)

HLH is a life-threatening condition that is characterized by overactivation of the immune system. HLH can cause fever, enlarged liver and spleen, low blood cell counts, and other symptoms.

Diagnosis of XLP-1

XLP-1 can be diagnosed through genetic testing, which involves analyzing the SH2D1A gene for mutations. Next-generation sequencing (NGS) is a type of genetic testing that can sequence multiple genes simultaneously, allowing for faster and more comprehensive testing. NGS can detect small mutations, insertions, and deletions in the SH2D1A gene, making it a highly accurate diagnostic tool for XLP-1.

In addition to genetic testing, XLP-1 can also be diagnosed through clinical evaluation, including blood tests, imaging studies, and biopsy. A diagnosis of XLP-1 is typically made by a genetic counselor or a medical geneticist.

Cost of XLP-1 NGS Genetic Test

The cost of XLP-1 NGS Genetic Test in India is typically around INR 20,000. The cost may vary depending on the laboratory and the type of genetic testing performed. Some insurance companies may cover the cost of genetic testing, so it is important to check with your insurance provider before undergoing testing.

Conclusion

XLP-1 is a rare genetic disorder that can cause a range of health complications. Genetic testing, such as NGS, can accurately diagnose XLP-1 and help patients receive appropriate medical care. The cost of XLP-1 NGS Genetic Testing in India is typically around INR 20,000, but may vary depending on the laboratory and insurance coverage. If you or your family member is experiencing symptoms of XLP-1, it is important to consult a medical professional for further evaluation and testing.

Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for SH2D1A Gene Lymphoproliferative syndrome, X-linked type 1 NGS Genetic Test

 Note: We offer free home sample collection for online bookings for SH2D1A Gene Lymphoproliferative syndrome, X-linked type 1 NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.