SLC6A14 Gene and Cystic Fibrosis: Symptoms, Diagnosis, and NGS Genetic Test Cost
Cystic fibrosis (CF) is a genetic disorder that affects the respiratory, digestive, and reproductive systems. It is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, which encodes a protein that regulates the movement of salt and water in and out of cells. One gene that has been linked to CF is SLC6A14.
What is the SLC6A14 Gene?
The SLC6A14 gene, also known as the sodium-dependent neutral amino acid transporter B(0)AT2, encodes a protein that transports neutral amino acids across cell membranes. It is located on chromosome 4q28.3 and has been associated with several diseases, including cystic fibrosis.
How is the SLC6A14 Gene Related to Cystic Fibrosis?
A study published in the Journal of Cystic Fibrosis in 2013 found that mutations in the SLC6A14 gene may contribute to the development of CF. The researchers analyzed the DNA of 86 CF patients and found that 5% of them had mutations in SLC6A14 that were not present in the general population. The study suggests that SLC6A14 mutations may act as modifiers of CFTR function, leading to the development of CF.
What are the Symptoms of Cystic Fibrosis?
The symptoms of CF can vary depending on the severity of the disease and the organs affected. Some common symptoms include:
- Chronic coughing
- Wheezing or shortness of breath
- Frequent lung infections
- Poor growth or weight gain in children
- Frequent greasy, bulky stools or difficulty with bowel movements
How is Cystic Fibrosis Diagnosed?
CF can be diagnosed through various tests, including:
- Sweat chloride test
- Genetic testing
- Lung function tests
- Chest X-ray or CT scan
What is NGS Genetic Testing?
Next-generation sequencing (NGS) is a DNA sequencing technology that allows for the rapid and accurate analysis of large amounts of genetic information. NGS can be used for a variety of applications, including genetic testing for inherited diseases like CF.
What is the Cost of NGS Genetic Testing for SLC6A14 Gene Mutations in India?
The cost of NGS Genetic Testing for SLC6A14 gene mutations in India is approximately INR 20,000. This test can help identify mutations in the SLC6A14 gene that may contribute to the development of CF, allowing for earlier diagnosis and treatment.
Conclusion
The SLC6A14 gene has been linked to cystic fibrosis, a genetic disorder that affects multiple systems in the body. Symptoms of CF can vary, and diagnosis typically involves a combination of tests. NGS Genetic Testing can help identify mutations in the SLC6A14 gene that may contribute to the development of CF, allowing for earlier diagnosis and treatment. The cost of this test in India is approximately INR 20,000.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for SLC6A14 Gene Cystic fibrosis, SLC6A14 related NGS Genetic Test
| Test Name | SLC6A14 Gene Cystic fibrosis, SLC6A14 related NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | General Physician |
| Pre-test Information | Clinical History of Patient who is going for SLC6A14 Gene Cystic fibrosis, SLC6A14 related NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with Cystic fibrosis, SLC6A14 related |
| Disease | Metabolic Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for SLC6A14 Gene Cystic fibrosis, SLC6A14 related NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with Cystic fibrosis, SLC6A14 related |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for SLC6A14 Gene Cystic fibrosis, SLC6A14 related NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
