TGFBR2 Gene and Marfan Syndrome: Symptoms, Diagnosis, and NGS Genetic Test Cost
Marfan syndrome is a genetic disorder that affects the connective tissue in the body, including the heart, blood vessels, bones, and joints. The condition is caused by mutations in the TGFBR2 gene, which provides instructions for making a protein that is involved in cell signaling and the regulation of cell growth and division. Mutations in this gene disrupt the normal function of the protein, leading to the characteristic features of Marfan syndrome.
Symptoms of Marfan Syndrome
Marfan syndrome can affect various parts of the body, and the severity of symptoms can vary widely among affected individuals. Some of the most common features of Marfan syndrome include:
- Tall stature and long limbs
- Abnormal curvature of the spine
- Joint hypermobility
- Stretch marks on the skin
- Eye problems, such as nearsightedness, dislocated lens, and early onset cataracts
- Cardiovascular problems, such as aortic aneurysm, mitral valve prolapse, and arrhythmias
Diagnosis of Marfan Syndrome
Diagnosis of Marfan syndrome is based on a combination of physical examination, family history, and genetic testing. A doctor may look for signs of the condition, such as aortic dilation, lens dislocation, and joint hypermobility. They may also ask about family history of Marfan syndrome or related conditions. Genetic testing can confirm a diagnosis of Marfan syndrome by identifying mutations in the TGFBR2 gene.
TGFBR2 Related NGS Genetic Test Cost
The TGFBR2 gene can be analyzed using next-generation sequencing (NGS) technology, which allows for the simultaneous analysis of multiple genes. This type of genetic testing can identify mutations in the TGFBR2 gene that are associated with Marfan syndrome. The cost of TGFBR2 related NGS Genetic Test in India is typically around INR 20,000.
Conclusion
Marfan syndrome is a genetic disorder that affects the connective tissue in the body and is caused by mutations in the TGFBR2 gene. Symptoms of the condition can vary widely, but may include tall stature, joint hypermobility, and cardiovascular problems. Diagnosis of Marfan syndrome is based on a combination of physical examination, family history, and genetic testing. Next-generation sequencing technology can be used to analyze the TGFBR2 gene and identify mutations associated with Marfan syndrome, with a typical cost of INR 20,000 in India.
If you suspect that you or a loved one may have Marfan syndrome, it is important to speak with a doctor or genetic counselor to discuss testing and treatment options. DNA Labs India offers TGFBR2 related NGS Genetic Testing for Marfan syndrome and other genetic conditions.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for TGFBR2 Gene Marfan syndrome, TGFBR2 related NGS Genetic Test
| Test Name | TGFBR2 Gene Marfan syndrome, TGFBR2 related NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Dermatologist |
| Pre-test Information | Clinical History of Patient who is going for TGFBR2 Gene Marfan syndrome, TGFBR2 related NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TGFBR2 Gene Marfan syndrome, TGFBR2 related NGS Genetic Test gene TGFBR2 |
| Disease | Osteology Dermatology Immunology Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for TGFBR2 Gene Marfan syndrome, TGFBR2 related NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TGFBR2 Gene Marfan syndrome, TGFBR2 related NGS Genetic Test gene TGFBR2 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for TGFBR2 Gene Marfan syndrome, TGFBR2 related NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
