Skip to main content
DNA Labs India

Tissue Transglutaminase (tTG) Antibody IgG Test

DNA Labs India | ISO 9001:2015 Certified

Tissue Transglutaminase (tTG) Antibody IgG Test

Short Name: tTG IgG Test

Also known as: tTG IgG Antibody Test, Celiac Disease Screening Test, Anti-Tissue Transglutaminase IgG Test

Tissue Transglutaminase (tTG) Antibody IgG Test test available at DNA Labs India for ₹1,170. Uses Enzyme Immunoassay on Serum samples. Results in Same-day results available for samples received by 9 AM Thursday; reports delivered via online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.

Blood Test🏠 Home Collection

🩺 Medically Reviewed By

Overview

To diagnose celiac disease and dermatitis herpetiformis, monitor adherence to a gluten-free diet, and assess for gluten-related autoimmune conditions.

Test Code
1443
Price
₹1,170
Sample Type
Serum
Result Time
Same-day results available for samples received by 9 AM Thursday; reports delivered via online portal, email, or WhatsApp.
Fasting Required
No
Method
Enzyme Immunoassay
Step 1

Sample Collection

No special preparation required

Method: Venipuncture

Step 2

Laboratory Analysis

A healthcare professional will draw a blood sample from a vein in your arm using standard phlebotomy procedures.

Step 3

Report Delivery

Apply pressure with a bandage to the puncture site to stop bleeding. Normal activities can be resumed immediately.

Timeline: Same-day results available for samples received by 9 AM Thursday; reports delivered via online portal, email, or WhatsApp.

Patient Instructions

1
Before the Test:No special preparation required; continue normal diet unless advised otherwise by your doctor.
2
During the Test:A standard blood draw procedure takes only a few minutes with minimal discomfort.
3
After the Test:You may experience minor bruising at the puncture site. Apply pressure and resume normal activities.

About This Test

Who Should Get This Test

To diagnose celiac disease and dermatitis herpetiformis, monitor adherence to a gluten-free diet, and assess for gluten-related autoimmune conditions.

How to Prepare

  • Sample must be refrigerated or frozen during transport to maintain stability

Doctor's Notes

Reviewed by — MBBS, MD (General Medicine) · Reg. No. 8052

"The tTG IgG test is essential for diagnosing celiac disease, especially in patients with IgA deficiency, and helps monitor dietary compliance."

Last medically reviewed: September 7, 2026

Test Parameters & Specifications

Sample TypeSerum
Sample Volume2 mL (1 mL min.)
ContainerSST (Serum Separator Tube)
Collection MethodVenipuncture

Sample Stability

Room Temperature: 8 hours
Refrigerated: 48 hours
Frozen: 4 weeks
Sample Rejection Criteria:
  • Hemolyzed or lipemic sample
  • Insufficient sample volume (< 1 mL)
  • Improperly stored or labeled sample

Understanding Your Results

Results of the tTG IgG test are interpreted based on the antibody levels detected, helping to assess the likelihood of celiac disease or related conditions.
📊

Negative (< 20 U/mL)

No tTG IgG antibodies detected, suggesting no active celiac disease or successful adherence to a gluten-free diet.

📊

Weak Positive (20-30 U/mL)

Borderline levels; further testing with tTG IgA or DGP antibodies, or repeat testing after gluten challenge, may be recommended.

📊

Positive (> 30 U/mL)

Elevated tTG IgG antibodies indicate likely celiac disease or dermatitis herpetiformis; confirmation with endoscopy and biopsy is advised.

⚠️ When to Consult a Doctor:

Consult your doctor if your test results are positive, if symptoms persist despite a gluten-free diet, or if you have a family history of celiac disease.

Limitations

  • tTG IgG test may have lower specificity compared to tTG IgA in patients with normal IgA levels
  • Results alone cannot confirm celiac disease; endoscopy and biopsy are often required for definitive diagnosis

Risks & Considerations

  • Minor bruising or soreness at the puncture site
  • Rarely, dizziness or fainting during blood draw
  • Extremely low risk of infection

Interfering Factors

  • Recent gluten intake may affect antibody levels
  • Other autoimmune conditions can cause cross-reactivity
  • Immunosuppressive medications may alter results

Compare With Similar Tests

TestTissue Transglutaminase (tTG) Antibody IgG TesttTG IgA Antibody TestAnti-Endomysial Antibody (EMA) TestDeamidated Gliadin Peptide (DGP) Antibody Test
ComparisonTissue Transglutaminase (tTG) Antibody IgG Test

Frequently Asked Questions

What is the tTG IgG test?
The tTG IgG test measures IgG antibodies against tissue transglutaminase in the blood, helping diagnose celiac disease and related conditions.
Why is this test done?
It is done to diagnose celiac disease, screen for dermatitis herpetiformis, monitor a gluten-free diet, and assess gluten-related autoimmune disorders.
How is the tTG IgG test performed?
A blood sample is drawn from a vein in your arm and analyzed in a lab using enzyme immunoassay to detect antibody levels.
Is fasting required for the tTG IgG test?
No, fasting is not required. You can eat and drink normally before the test.
What do the results mean?
Negative results suggest no celiac disease or good dietary control, while positive results indicate possible celiac disease and may require further confirmation.
How accurate is the tTG IgG test?
The test has high sensitivity (around 98.5% when combined with tTG IgA), but accuracy can vary based on individual factors and lab methods.
What is the cost of the tTG IgG test in India?
The test costs INR 1170 at DNA Labs India, with free home sample collection available in many cities.
Is home collection available for this test?
Yes, DNA Labs India offers free home sample collection for online bookings across major cities in India.
How long does it take to get the results?
Results are typically available on the same day if the sample is received by 9 AM Thursday, and delivered via online portal, email, or WhatsApp.
Can this test be used to monitor a gluten-free diet?
Yes, declining tTG IgG levels over time can indicate adherence to a gluten-free diet, helping monitor treatment effectiveness.
What is the difference between tTG IgG and tTG IgA tests?
tTG IgA is more specific for celiac disease in patients with normal IgA levels, while tTG IgG is useful for those with IgA deficiency or when IgA tests are negative.
Should I stop eating gluten before the test?
No, do not stop eating gluten before the test, as it may lead to false-negative results. Continue your normal diet unless advised by your doctor.
Worried about the process? Our certified phlebotomists collect thousands of samples every month across India. The process takes under 5 minutes and is virtually painless. Questions? Message us on WhatsApp — we're here 7 days a week.

Related Tests

For Hospitals & Clinics

Reference Laboratory Services

We serve as a reference laboratory for hospitals and clinics across India. Send samples from your facility with same-day pickup, priority processing, and results delivered through our online portal. Competitive institutional pricing available.

LIMS Integration

Your Data Privacy

Your medical data is protected under Indian law.

Stored in India: All patient records are stored on servers located in India. No data is transferred outside the country.

DPDP Act Compliant: Under the Digital Personal Data Protection Act 2023, you can request deletion of your records at any time by contacting support.

Book Your Test

Enter your details and we'll connect you within 15 minutes.

🧬

Quick Connect

Enter your mobile number and we’ll connect you with the team.

+91

✅ Connecting you now...

🔒 Your number is used to respond to this request.