Understanding the TLR5 Gene and its Role in Legionnaire Disease: NGS Genetic Test Cost INR 20000
Legionnaire disease, also known as legionellosis, is a severe type of pneumonia caused by the Legionella bacteria. This bacterium is commonly found in freshwater environments, such as rivers, lakes, and hot springs. Legionnaire disease is contracted when a person inhales small droplets of water containing the bacteria. The disease can affect anyone, but certain individuals may be more susceptible to the disease due to their genetics, specifically their TLR5 gene.
The TLR5 Gene and Legionnaire Disease Susceptibility
The TLR5 gene codes for a protein that plays a crucial role in the immune response to bacterial infections. This protein recognizes and binds to a specific component of the bacterial flagellum, which is a whip-like structure that helps bacteria move. When the TLR5 protein binds to the flagellum, it triggers an immune response that helps the body fight off the infection.
Research has shown that individuals with a specific variation in the TLR5 gene may be more susceptible to Legionnaire disease. This variation, known as TLR5 rs5744168, is associated with a decreased ability to recognize and respond to the Legionella bacteria.
Symptoms and Diagnosis of Legionnaire Disease
The symptoms of Legionnaire disease can vary, but typically include:
- Fever
- Cough
- Shortness of breath
- Muscle aches
- Headache
- Fatigue
Diagnosis of Legionnaire disease typically involves a combination of clinical evaluation and laboratory testing. Blood and urine tests can be used to detect the presence of the Legionella bacteria, and imaging tests such as chest X-rays may be used to evaluate the extent of the infection.
NGS Genetic Test for TLR5 Gene and Legionnaire Disease Susceptibility
If you are concerned about your risk of Legionnaire disease, a Next-Generation Sequencing (NGS) Genetic Test can provide valuable information about your TLR5 gene. This test analyzes your DNA to identify any variations in the TLR5 gene that may increase your susceptibility to Legionnaire disease. The cost of the NGS Genetic Test for TLR5 gene and Legionnaire disease susceptibility is INR 20000.
By identifying your risk for Legionnaire disease, you can take steps to reduce your exposure to the Legionella bacteria, such as avoiding high-risk environments and practicing good hygiene. You can also work with your healthcare provider to develop a personalized plan for managing your health and reducing your risk of infection.
Conclusion
Legionnaire disease can be a severe and potentially life-threatening infection, but by understanding your risk factors, you can take steps to protect yourself. If you are concerned about your risk of Legionnaire disease, consider a NGS Genetic Test to analyze your TLR5 gene and identify any variations that may increase your susceptibility. The cost of this test is INR 20000, and it can provide valuable information to help you manage your health and reduce your risk of infection.
Before getting tested ask for Raw Data, FASTQ, and VCF files along with clinical test report from DNA Testing Lab. DNA Labs India is the Only lab that is transparent and will share Raw Data, FASTQ, and VCF files along with the conclusive clinical report for TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test
| Test Name | TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Pediatrics |
| Pre-test Information | Clinical History of Patient who is going for TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test gene TLR5 |
| Disease | Dysmorphology |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test gene TLR5 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for TLR5 Gene Legionnaire disease, susceptibility to NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
