Toxoplasma Antibody IgG Test
Short Name: Toxo IgG
Also known as: Toxoplasma IgG Antibody Test, Toxoplasma gondii IgG Test, Toxo IgG Antibody Test, Toxoplasma Serology IgG, Anti-Toxoplasma IgG Test
Toxoplasma Antibody IgG Test test available at DNA Labs India for ₹679. Uses CLIA (Chemiluminescent Immunoassay) on Serum samples. Results in Reports are typically available within the same day or next working day. Digital reports can be accessed via the online portal, email, or WhatsApp.. Free home collection in 300+ cities across India.
🩺 Medically Reviewed By
Dr Kothari Ramesh Shantilal
Consultant Microbiologist · Reg: 27670
Last reviewed: September 7, 2026
Overview
The Toxoplasma Antibody IgG Test is used to determine whether an individual has been previously exposed to the Toxoplasma gondii parasite. It helps clinicians assess immune status, evaluate the risk of congenital transmission during pregnancy, monitor immunocompromised patients for reactivation of latent infection, and support the diagnosis of ocular toxoplasmosis and toxoplasmic encephalitis. The test is an essential component of the TORCH panel workup in prenatal screening.
- Test Code
- 1447
- CPT Code
- 86777
- ICD Code
- B58.9
- Price
- ₹679
- Sample Type
- Serum
- Result Time
- Reports are typically available within the same day or next working day. Digital reports can be accessed via the online portal, email, or WhatsApp.
- Fasting Required
- No
- Method
- CLIA (Chemiluminescent Immunoassay)
Sample Collection
No special preparation, fasting, or dietary restrictions are required before this test. Inform your healthcare provider about any medications, recent vaccinations, or immunoglobulin therapy, as these may affect results.
Method: Venipuncture
Laboratory Analysis
A trained phlebotomist will collect approximately 2 mL of blood from a vein in your arm using a sterile needle and SST (Serum Separator Tube). The procedure typically takes less than 5 minutes and may cause minimal discomfort at the puncture site.
Report Delivery
Apply gentle pressure with cotton or a bandage at the puncture site for a few minutes to prevent bruising. You can resume normal activities immediately. Mild soreness at the collection site is common and resolves within a day.
Timeline: Reports are typically available within the same day or next working day. Digital reports can be accessed via the online portal, email, or WhatsApp.
Patient Instructions
About This Test
Who Should Get This Test
The Toxoplasma Antibody IgG Test is used to determine whether an individual has been previously exposed to the Toxoplasma gondii parasite. It helps clinicians assess immune status, evaluate the risk of congenital transmission during pregnancy, monitor immunocompromised patients for reactivation of latent infection, and support the diagnosis of ocular toxoplasmosis and toxoplasmic encephalitis. The test is an essential component of the TORCH panel workup in prenatal screening.
How to Prepare
- No fasting or special preparation is required before sample collection
- Stay well hydrated before blood draw for easier venipuncture
- Inform the phlebotomist about any anticoagulant therapy or bleeding disorders
- Sample collected in SST (Serum Separator Tube) – 2 mL minimum serum required
- Ship sample refrigerated (2-8°C) or frozen if transport time exceeds stability limits
- Free home sample collection is available across 300+ cities in India
Doctor's Notes
Reviewed by Dr Kothari Ramesh Shantilal — MBBS, MD (Microbiology) · Reg. No. 27670
"The Toxoplasma IgG antibody test is a valuable screening tool for determining past exposure to Toxoplasma gondii. In my clinical practice, I routinely order this test for pregnant women during their first antenatal visit to assess immunity, for immunocompromised patients including those living with HIV and transplant recipients to evaluate risk of reactivation, and for patients presenting with unexplained lymphadenopathy, chorioretinitis, or encephalitis. A positive IgG result with a negative IgM result generally indicates a past infection and established immunity, which is reassuring in most clinical scenarios. However, in immunocompromised individuals, persistently high or rising IgG titers alongside neurological or ophthalmic symptoms warrant further investigation including PCR testing and neuroimaging. It is important to interpret IgG results in conjunction with IgM findings and the patient's clinical context. Equivocal results should be confirmed with repeat testing after 2-3 weeks. Patients with positive results and active symptoms should consult an infectious disease specialist for comprehensive evaluation and management."
Last medically reviewed: September 7, 2026
Test Parameters & Specifications
Sample Stability
- Hemolyzed or grossly lipemic samples
- Samples collected in incorrect tube type (not SST)
- Samples received at room temperature beyond 2 hours
- Insufficient sample volume (less than 1 mL serum)
- Samples with patient identification discrepancies
- Thawed frozen samples that have been refrozen
Understanding Your Results
No evidence of past or recent Toxoplasma infection. The individual is susceptible to new infection.
Clinical action: Advise preventive measures especially in pregnant women. Repeat testing if clinical suspicion is high.
Past infection with established immunity. IgG antibodies persist for life after exposure.
Clinical action: Generally indicates immunity. In pregnancy, reassurance that prior infection has conferred immunity. No further action usually needed.
May indicate recent or active infection. IgM can persist for months to over a year in some cases.
Clinical action: Confirm with IgG avidity testing. In pregnancy, refer to specialist for risk assessment and possible treatment. In immunocompromised, evaluate for active disease with PCR and imaging.
Possible very early acute infection before IgG seroconversion, or false-positive IgM.
Clinical action: Repeat both IgG and IgM testing after 2-3 weeks. Confirm with reference laboratory if needed.
Borderline result; infection status cannot be determined with certainty.
Clinical action: Repeat testing after 2-3 weeks. Consider confirmatory testing at a reference laboratory.
Consult your doctor if your Toxoplasma IgG result is positive, especially if you are pregnant, planning pregnancy, immunocompromised, or experiencing symptoms such as fever, swollen lymph nodes, blurred vision, confusion, or seizures. A positive result with concurrent positive IgM warrants urgent medical evaluation. Equivocal results should also be discussed with your healthcare provider for appropriate follow-up testing.
Limitations
- ⚠This test detects IgG antibodies only and cannot distinguish between active and past infection on its own
- ⚠IgG antibodies persist for life; a single positive result does not confirm recent or active infection
- ⚠Equivocal results require repeat testing after 2-3 weeks for confirmation
- ⚠Should be interpreted in conjunction with IgM antibody testing, clinical findings, and patient history
- ⚠Cannot be used as the sole diagnostic test in immunocompromised patients; PCR testing may be required
- ⚠Results may vary between laboratories depending on the assay kit and method used
Risks & Considerations
- ●Minimal risk associated with blood draw
- ●Mild pain, bruising, or swelling at the puncture site
- ●Very rare risk of infection at the collection site
- ●Fainting or dizziness in individuals sensitive to blood draws
Interfering Factors
- ●Hemolyzed, lipemic, or icteric serum samples may affect test accuracy
- ●Recent blood transfusions or immunoglobulin therapy may cause false-positive results
- ●Immunosuppressive therapy may reduce antibody production leading to false-negative results
- ●Cross-reactivity with other parasitic infections is possible but uncommon with modern CLIA assays
- ●Very early infection before seroconversion may yield false-negative results
Compare With Similar Tests
| Test | Toxoplasma Antibody IgG Test | Toxoplasma Antibody IgM Test | Toxoplasma IgG Avidity Test | Toxoplasma PCR Test | TORCH Panel Test |
|---|---|---|---|---|---|
| Comparison | Toxoplasma Antibody IgG Test |
Frequently Asked Questions
What is the Toxoplasma Antibody IgG Test?
Why is this test important during pregnancy?
What does a positive Toxoplasma IgG result mean?
What is the difference between IgG and IgM antibody tests?
Do I need to fast before this test?
How is the blood sample collected?
What is the cost of the Toxoplasma Antibody IgG Test in India?
How long does it take to get the results?
Can a positive IgG test indicate an active infection?
Who should get this test done?
Is home sample collection available for this test?
What happens if my test results are equivocal?
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