TTC21B Gene Short-rib thoracic dysplasia type 4 with or without polydactyly NGS Genetic Test
Short-rib thoracic dysplasia (SRTD) is a group of rare genetic disorders that affect the development of bones and other tissues in the body. SRTD is caused by mutations in different genes that are involved in the formation and maintenance of bone and cartilage. One of the genes associated with SRTD is TTC21B.
TTC21B gene mutations are known to cause Short-rib thoracic dysplasia type 4 with or without polydactyly (SRTD4), a severe form of SRTD that affects the bones and other tissues in the chest, as well as the limbs and other parts of the body.
Symptoms of SRTD4
The symptoms of SRTD4 can vary from person to person, but typically include:
- Shortening of the ribs
- Narrowing of the chest
- Underdeveloped lungs
- Polydactyly (extra fingers or toes)
- Abnormalities of the limbs
- Facial abnormalities
- Low birth weight
- Respiratory distress
Diagnosis of SRTD4
SRTD4 can be diagnosed before birth using ultrasound imaging. After birth, a physical examination can reveal some of the physical characteristics associated with SRTD4. Genetic testing can confirm a diagnosis of SRTD4 by identifying mutations in the TTC21B gene.
NGS Genetic Test for SRTD4
NGS (Next Generation Sequencing) genetic testing is a powerful tool for identifying genetic mutations associated with SRTD4. This type of testing can analyze multiple genes at once, including TTC21B, to provide a comprehensive analysis of genetic mutations that may be contributing to the development of SRTD4.
Cost of NGS Genetic Test for SRTD4 in India
The cost of NGS genetic testing for SRTD4 in India can vary depending on the specific test and the laboratory performing the test. On average, the cost of NGS genetic testing for SRTD4 is around INR 20,000.
Conclusion
SRTD4 is a rare genetic disorder that can have serious consequences for affected individuals. Genetic testing, including NGS testing, can provide valuable information for diagnosis and treatment of SRTD4. If you suspect that you or a loved one may be affected by SRTD4, talk to your doctor about genetic testing options.
| Test Name | TTC21B Gene Short-rib thoracic dysplasia type 4 with or without polydactyly NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card |
| Test type | Pediatrics |
| Pre-test Information | Clinical History of Patient who is going for TTC21B Gene Short-rib thoracic dysplasia type 4 with or without polydactyly NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TTC21B Gene Short-rib thoracic dysplasia type 4 with or without polydactyly NGS Genetic Test gene TTC21B |
| Disease | Dysmorphology |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for TTC21B Gene Short-rib thoracic dysplasia type 4 with or without polydactyly NGS Genetic Test. A Genetic Counselling session to draw a pedigree chart of family members affected with TTC21B Gene Short-rib thoracic dysplasia type 4 with or without polydactyly NGS Genetic Test gene TTC21B |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for TTC21B Gene Short-rib thoracic dysplasia type 4 with or without polydactyly NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
