MATERNAL SERUM SCREEN 2: ADVANCED REFLEX TO MATERNAL BLOOD FOR FETAL DNA (MBFD) CHROMOSOME 21 Test
Maternal serum screening is a test that helps to determine the risk of certain birth defects in a developing fetus. The test is done during pregnancy and measures the levels of certain substances in the mother’s blood. One of the most common tests is called the Maternal Serum Screen 2 (MSS2), which includes an advanced reflex to maternal blood for fetal DNA (MBFD) chromosome 21 test. This test is used to screen for Down syndrome and other chromosomal abnormalities.
Symptoms of Down Syndrome
Down syndrome is a genetic condition that affects a person’s physical and mental development. Some common symptoms of Down syndrome include:
- Small head and ears
- A flat nose and upward slanting eyes
- A short neck and small mouth
- A broad, short hands with a single crease in the palm
- A short stature and low muscle tone
- An intellectual disability
It’s important to note that not all people with Down syndrome will exhibit all of these symptoms. Some may have only a few of these characteristics, while others may have more severe symptoms.
Diagnosis of Down Syndrome
The diagnosis of Down syndrome is typically made after birth, based on physical characteristics and the results of genetic testing. However, the MBFD chromosome 21 test can be done during pregnancy to screen for the condition.
The test is done by taking a sample of the mother’s blood and analyzing it for the presence of fetal DNA. If the test comes back positive for an increased risk of Down syndrome, further testing may be recommended to confirm the diagnosis.
Cost of the MBFD Chromosome 21 Test
The cost of the MBFD chromosome 21 test varies depending on the provider and location. In India, the test typically costs around INR 3500.
Conclusion
The Maternal Serum Screen 2 with an advanced reflex to maternal blood for fetal DNA (MBFD) chromosome 21 test is an important tool in screening for Down syndrome and other chromosomal abnormalities during pregnancy. If you’re pregnant and want to learn more about this test, talk to your healthcare provider.
At DNA Labs India, we offer a wide range of genetic testing services, including the MBFD chromosome 21 test. Our team of experts is dedicated to providing accurate and reliable results to help you make informed decisions about your health and the health of your baby. Contact us today to learn more.
| Test Name | Maternal Serum Screen 2: Advanced Reflex to Maternal Blood for Fetal DNA (MBFD) Chromosome 21 Test |
|---|---|
| Sample type | 3 mL (1.5 mL min.) serum from 1 SST. Provide maternal Date of birth (dd/mm/yy); LMP or Ultrasound; Number of Fetuses (Single/Twins); Diabetic status and Body Weight in Kg, IVF, Smoking & Previous history of Trisomy 21 pregnancy. Ship refrigerated or frozen. All positive results to submit 10 mL whole blood in a Special tube available from LPL for MBFD-21/NIPT along with duly filled Maternal Serum Screen 2 reflex to MBFD-21 consent form (Form 12). Ship refrigerated. DO NOT FREEZE. Valid between 10-13 weeks gestation. |
| Test type | Gynecologist |
| Pre-test Information | Provide maternal Date of birth (dd/mm/yy); LMP or Ultrasound; Number of Fetuses (Single/Twins); Diabetic status and Body Weight in Kg, IVF, Smoking & Previous history of Trisomy 21 pregnancy. All positive results to submit 10 mL whole blood in a Special tube available from LPL for MBFD-21/NIPT along with duly filled Maternal Serum Screen 2 reflex to MBFD-21 consent form (Form 12). Valid between 10-13 weeks gestation. |
| Disease | Prenatal Diagnosis |
| Method | Chemiluminescent Immunoassay, DNA Sequencing |
| Purpose | *PAPP-A *Free Beta HCG *Risk Evaluation *MBFD-21 |
| Preparation | Room Temperature: 6 hrs, Refrigerator:24 hrs, Frozen: 2 months |
| Fasting | Provide maternal Date of birth (dd/mm/yy); LMP or Ultrasound; Number of Fetuses (Single/Twins); Diabetic status and Body Weight in Kg, IVF, Smoking & Previous history of Trisomy 21 pregnancy. All positive results to submit 10 mL whole blood in a Special tube available from LPL for MBFD-21/NIPT along with duly filled Maternal Serum Screen 2 reflex to MBFD-21 consent form (Form 12). Valid between 10-13 weeks gestation. |
| Get Reports | Dual test: Sample Mon through Sat by 9 am; Report Same dayMBFD-21: Sample Tue by 9 am; Report Next Tue |
| Test Price | INR ₹ 3500 |
Note: We offer free home sample collection for online bookings for Maternal Serum Screen 2: Advanced Reflex to Maternal Blood for Fetal DNA (MBFD) Chromosome 21 Test and the test costs a special discounted price of 3500 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
