CHRNA4 Gene Epilepsy – Nocturnal Frontal Lobe Type 1 NGS Genetic Test Cost INR 20000: Symptoms and Diagnosis
Epilepsy is a neurological disorder that affects millions of people worldwide. It is characterized by recurrent seizures, which are caused by abnormal electrical activity in the brain. Epilepsy can be caused by a variety of factors, including genetics, brain injury, infection, and more.
One specific genetic factor that has been linked to epilepsy is the CHRNA4 gene. This gene is responsible for producing a protein called the alpha-4 subunit of the nicotinic acetylcholine receptor, which is involved in the transmission of nerve signals in the brain. Mutations in the CHRNA4 gene have been found to cause a specific type of epilepsy known as nocturnal frontal lobe epilepsy type 1 (NFLE1).
Symptoms of CHRNA4 Gene Epilepsy
The symptoms of CHRNA4 gene epilepsy are similar to those of other types of epilepsy. They include:
- Recurrent seizures
- Uncontrolled movements or convulsions
- Loss of consciousness
- Confusion or disorientation after a seizure
- Memory problems
- Behavioral changes
However, one characteristic feature of NFLE1 is that the seizures typically occur during sleep, specifically during the first few hours of the night. These seizures can be difficult to diagnose, as they may not be visible to the person experiencing them or to others.
Diagnosis of CHRNA4 Gene Epilepsy
Diagnosing CHRNA4 gene epilepsy requires a combination of clinical evaluation and genetic testing. A doctor will typically perform a neurological exam and ask about the patient’s medical history and symptoms. They may also order an electroencephalogram (EEG), which measures the electrical activity in the brain.
In addition, genetic testing can be used to identify mutations in the CHRNA4 gene. Next-generation sequencing (NGS) is a type of genetic testing that can rapidly sequence large amounts of DNA. This technology can be used to identify genetic mutations associated with NFLE1 and other types of epilepsy.
NGS Genetic Test Cost
The cost of an NGS Genetic Test for CHRNA4 gene epilepsy is typically around INR 20000. However, the actual cost may vary depending on the specific testing facility and any additional tests that may be required.
Conclusion
CHRNA4 gene epilepsy is a specific type of epilepsy that is caused by mutations in the CHRNA4 gene. It is characterized by seizures that occur during sleep, making it difficult to diagnose. However, with a combination of clinical evaluation and genetic testing, it is possible to identify mutations in the CHRNA4 gene and diagnose NFLE1. The cost of NGS Genetic Testing for CHRNA4 gene epilepsy is typically around INR 20000.
If you suspect that you or a loved one may have CHRNA4 gene epilepsy, it is important to seek medical attention and discuss the possibility of genetic testing with a healthcare professional.
Epilepsy, Nocturnal Frontal Lobe Type 1 (ENFL1), also known as autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE), is a rare genetic form of epilepsy characterized by seizures that predominantly occur during sleep. Mutations in the CHRNA4 gene have been associated with ENFL1.
| Test Name | CHRNA4 Gene Epilepsy, nocturnal frontal lobe type 1 NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Test type | Neurologist |
| Pre-test Information | Clinical History of Patient who is going for CHRNA4 Gene Epilepsy, nocturnal frontal lobe type 1 NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with CHRNA4 Gene Epilepsy, nocturnal frontal lobe type 1 |
| Disease | Neurological Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for CHRNA4 Gene Epilepsy, nocturnal frontal lobe type 1 NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with CHRNA4 Gene Epilepsy, nocturnal frontal lobe type 1 |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for CHRNA4 Gene Epilepsy, nocturnal frontal lobe type 1 NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
