EIF2B3 Gene Leukoencephalopathy with Vanishing White Matter NGS Genetic Test

Leukoencephalopathy with vanishing white matter (VWM) is a rare genetic disorder that affects the central nervous system. It is caused by mutations in the EIF2B3 gene, which provides instructions for making a protein that is essential for the normal functioning of brain cells. VWM can be diagnosed using Next-Generation Sequencing (NGS) Genetic Test, which detects mutations in the EIF2B3 gene. The cost of this test is INR 20,000.

Symptoms of VWM

The symptoms of VWM usually appear in early childhood, but in some cases, they may not appear until later in life. The severity of symptoms can vary widely, even among individuals with the same mutation. Some common symptoms of VWM include:

• Difficulty walking or controlling movements
• Loss of vision or blindness
• Seizures
• Behavioral changes
• Developmental delays
• Intellectual disability
• Headaches
• Progressive muscle stiffness and weakness
• Loss of coordination
• Coma or death

Diagnosis of VWM

VWM can be diagnosed by performing a genetic test that looks for mutations in the EIF2B3 gene. The NGS Genetic Test is the most accurate and reliable test available for diagnosing VWM. This test can detect all known mutations in the EIF2B3 gene, making it possible to confirm a diagnosis of VWM even in cases where the symptoms are atypical. This test is usually performed on a blood sample, but in some cases, it may be performed on other tissue samples, such as skin cells or muscle tissue.

Cost of NGS Genetic Test for VWM

The cost of the NGS Genetic Test for VWM is INR 20,000. This cost includes the cost of the test itself as well as the cost of any necessary follow-up appointments or consultations with a genetic counselor. Some insurance plans may cover the cost of this test, but coverage varies widely depending on the plan and the individual’s specific circumstances. It is important to check with your insurance provider to determine if this test is covered and what out-of-pocket costs you may incur.

Conclusion

VWM is a rare genetic disorder that can cause a wide range of symptoms, including difficulty walking, loss of vision, seizures, and developmental delays. It is caused by mutations in the EIF2B3 gene, which can be detected using the NGS Genetic Test. The cost of this test is INR 20,000. If you or a loved one is experiencing symptoms of VWM, it is important to speak with a healthcare provider or genetic counselor to determine if testing is appropriate.

At DNA Labs India, we offer a wide range of genetic testing services, including the NGS Genetic Test for VWM. Our team of experienced and knowledgeable genetic counselors can help you understand the testing process and what the results mean for you and your family. Contact us today to learn more about our services.

 Note: We offer free home sample collection for online bookings for EIF2B3 Gene Leukoencephalopathy with vanishing white matter NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.