EIF2B4 Gene Leukoencephalopathy with Vanishing White Matter NGS Genetic Test Cost INR: 20,000 Symptoms Diagnosis
Leukoencephalopathy with vanishing white matter (VWM) is a rare genetic disorder that affects the central nervous system. It is caused by mutations in the EIF2B1-5 genes, which encode the five subunits of the eukaryotic initiation factor 2B (eIF2B) complex. Among these genes, EIF2B4 is the most commonly mutated one. DNA Labs India offers an NGS Genetic Test for EIF2B4 gene mutations associated with VWM at a cost of INR 20,000.
Symptoms of VWM
VWM usually starts in early childhood and progresses slowly over time. The symptoms vary depending on the severity of the disease. Some common symptoms include:
- Difficulty walking and poor balance
- Loss of motor skills
- Speech problems
- Seizures
- Visual impairment
- Cognitive decline
- Behavioral changes
The severity and progression of symptoms can vary greatly among individuals with VWM, even within the same family.
Diagnosis of VWM
VWM is diagnosed through a combination of clinical evaluation, brain imaging, and genetic testing. Brain MRI scans can show characteristic changes in the white matter of the brain, which can help distinguish VWM from other leukodystrophies. Genetic testing is essential for confirming the diagnosis and identifying the specific EIF2B gene mutations responsible for the disease. DNA Labs India offers an NGS Genetic Test for EIF2B4 gene mutations associated with VWM at a cost of INR 20,000.
Genetic Testing for VWM
The NGS Genetic Test offered by DNA Labs India can detect mutations in the EIF2B4 gene that are associated with VWM. This test uses next-generation sequencing technology to analyze the entire coding region of the EIF2B4 gene, as well as adjacent intronic regions. The test has a high sensitivity and specificity, and can detect both known and novel mutations in the gene.
Genetic testing for VWM can provide important information for families affected by the disease. It can confirm the diagnosis, identify carriers of the mutation, and provide information about the risk of passing the mutation on to future generations. It can also help guide medical management and treatment decisions for individuals with VWM.
Conclusion
VWM is a rare genetic disorder that can cause significant neurological symptoms and disability. Genetic testing is essential for confirming the diagnosis and identifying the specific EIF2B gene mutations responsible for the disease. DNA Labs India offers an NGS Genetic Test for EIF2B4 gene mutations associated with VWM at a cost of INR 20,000. This test can provide important information for families affected by the disease and help guide medical management and treatment decisions.
If you suspect that you or a family member may have VWM, it is important to consult with a medical professional and consider genetic testing.
Contact DNA Labs India today to learn more about our NGS Genetic Test for EIF2B4 gene mutations associated with VWM.
| Test Name | EIF2B4 Gene Leukoencephalopathy with vanishing white matter NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Test type | Neurologist |
| Pre-test Information | Clinical History of Patient who is going for EIF2B4 Gene Leukoencephalopathy with vanishing white matter NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with EIF2B4 Gene Leukoencephalopathy with vanishing white matter |
| Disease | Neurological Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for EIF2B4 Gene Leukoencephalopathy with vanishing white matter NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with EIF2B4 Gene Leukoencephalopathy with vanishing white matter |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for EIF2B4 Gene Leukoencephalopathy with vanishing white matter NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
