CELSR2 Gene and Schizophrenia: Understanding the Link
Schizophrenia is a complex mental disorder that affects millions of people worldwide. While the exact causes of schizophrenia are not fully understood, research has shown that genetics plays a significant role in its development. One of the genes that have been linked to schizophrenia is the CELSR2 gene.
What is the CELSR2 gene?
The CELSR2 gene is a protein-coding gene that is involved in the development and functioning of the nervous system. It plays a crucial role in the formation and maintenance of neuronal connections in the brain. Studies have shown that mutations in the CELSR2 gene are associated with an increased risk of developing schizophrenia.
How is the CELSR2 gene linked to schizophrenia?
Research has found that the CELSR2 gene is involved in the regulation of the neurotransmitter dopamine, which is known to be dysregulated in individuals with schizophrenia. Dopamine is a chemical messenger that plays a crucial role in regulating mood, motivation, and reward processing. Studies have shown that individuals with schizophrenia have higher levels of dopamine in certain areas of the brain, which may contribute to the development of psychotic symptoms.
In addition to its role in dopamine regulation, the CELSR2 gene is also involved in the development of the prefrontal cortex, a brain region that is implicated in the cognitive and emotional impairments seen in individuals with schizophrenia.
CELSR2-related NGS Genetic Test for Schizophrenia
Advancements in genetic testing have made it possible to identify mutations in the CELSR2 gene that are associated with an increased risk of developing schizophrenia. The CELSR2-related NGS Genetic Test is a type of genetic testing that uses next-generation sequencing (NGS) technology to analyze an individual’s DNA for mutations in the CELSR2 gene.
The cost of the CELSR2-related NGS Genetic Test in India is INR 20,000. The test is performed using a small sample of blood or saliva and is non-invasive and painless. The results of the test can provide valuable information about an individual’s genetic risk for developing schizophrenia, which can inform treatment decisions and help individuals make informed decisions about their mental health.
Symptoms and Diagnosis of Schizophrenia
Schizophrenia is a complex mental disorder that can present with a range of symptoms. Some of the most common symptoms of schizophrenia include:
- Delusions
- Hallucinations
- Disordered thinking and speech
- Abnormal motor behavior
- Negative symptoms, such as apathy and social withdrawal
Diagnosing schizophrenia can be challenging, as there is no single test that can definitively diagnose the disorder. Instead, healthcare professionals rely on a combination of clinical evaluation, medical history, and diagnostic tests to make a diagnosis.
If you are experiencing symptoms of schizophrenia or are concerned about your risk for developing the disorder, it is important to speak with a healthcare professional. They can provide a comprehensive evaluation and help you make informed decisions about your mental health.
Conclusion
The CELSR2 gene is an important gene that is involved in the development and functioning of the nervous system. Mutations in this gene have been linked to an increased risk of developing schizophrenia. The CELSR2-related NGS Genetic Test is a valuable tool for identifying individuals who may be at an increased risk for developing schizophrenia. If you are concerned about your risk for developing schizophrenia, speak with a healthcare professional about your options for genetic testing and mental health evaluation.
| Test Name | CELSR2 Gene Schizophrenia, CELSR2 related NGS Genetic Test |
|---|---|
| Sample type | Blood or Extracted DNA or One drop Blood on FTA Card o |
| Test type | Neurologist |
| Pre-test Information | Clinical History of Patient who is going for CELSR2 Gene Schizophrenia, CELSR2 related NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with CELSR2 Gene Schizophrenia, CELSR2 related |
| Disease | Neurological Disorders |
| Method | NGS Technology |
| Purpose | NULL |
| Preparation | Ambient Room Temperature |
| Fasting | Clinical History of Patient who is going for CELSR2 Gene Schizophrenia, CELSR2 related NGS Genetic Test A Genetic Counselling session to draw a pedigree chart of family members affected with CELSR2 Gene Schizophrenia, CELSR2 related |
| Get Reports | 3 to 4 Weeks |
| Test Price | INR ₹ 20000 |
Note: We offer free home sample collection for online bookings for CELSR2 Gene Schizophrenia, CELSR2 related NGS Genetic Test and the test costs a special discounted price of 20000 INR across India. The cities where this service is available include Mumbai, Delhi, Bangalore, Hyderabad, Ahmedabad, Chennai, Kolkata, Surat, Pune, Jaipur, Lucknow, Kanpur, Nagpur, Indore, Thane, Bhopal, Visakhapatnam, Pimpri-Chinchwad, Patna, Vadodara, Ghaziabad, Ludhiana, Agra, Nashik, Faridabad, Meerut, Rajkot, Kalyan-Dombivali, Vasai-Virar, Varanasi, Srinagar, Aurangabad, Dhanbad, Amritsar, Navi Mumbai, Prayagraj, Howrah, Ranchi, Jabalpur, Gwalior, Coimbatore, Vijayawada, Jodhpur, Madurai, Raipur, Kota, Guwahati, Chandigarh, Thiruvananthapuram, Solapur, Hubballi-Dharwad, Tiruchirappalli, Tiruppur, Moradabad, Mysore, Bareily, Gurgaon, Aligarh, Jalandhar, Bhubaneswar, Salem, Mira-Bhayandar, Warangal , Guntur , Bhiwandi, Saharanpur, Gorakhpur, Bikaner, Amravati, Noida, Jamshedpur, Bhilai, Cuttack, Firozabad, Kochi, Nellore , Bhavnagar, Dehradun, Durgapur, Asansol, Rourkela, Nanded, Kolhapur, Ajmer, Akola, Gulbarga, Jamnagar, Ujjain, Loni, Siliguri, Jhansi, Ulhasnagar, Jammu, Sangli-Miraj & Kupwad, Mangalore, Erode10, Belgaum, Ambattur, Tirunelveli, Malegaon, Gaya, Jalgaon, Udaipur, Maheshtala, Davanagere, Kozhikode, Kurnool, Rajpur Sonarpur, Rajahmundry , Bokaro, South Dumdum, Bellary, Patiala, Gopalpur, Agartala, Bhagalpur, Muzaffarnagar, Bhatpara, Panihati, Latur, Dhule, Tirupati , Rohtak, Korba, Bhilwara, Berhampur, Muzaffarpur, Ahmednagar, Mathura, Kollam, Avadi, Kadapa, Kamarhati, Sambalpur, Bilaspur, Shahjahanpur, Satara, Bijapur, Rampur, Shivamogga, Chandrapur, Junagadh, Thrissur, Alwar, Bardhaman, Kulti, Kakinada, Nizamabad, Parbhani, Tumkur, Khammam, Ozhukarai, Bihar Sharif, Panipat, Darbhanga, Bally, Aizawl, Dewas, Ichalkaranji, Karnal, Bathinda, Jalna, Eluru, Kirari Suleman Nagar, Barasat, Purnia, Satna, Mau, Sonipat, Farrukhabad, Sagar, Rourkela, Durg, Imphal, Ratlam, Hapur, Arrah, Karimnagar, Anantapur, Etawah, Ambernath, North Dumdum, Bharatpur, Begusarai, New Delhi, Gandhidham, Baranagar, Tiruvottiyur, Puducherry, Sikar, Thoothukudi, Rewa, Mirzapur, Raichur, Pali, Ramagundam , Haridwar, Vijayanagaram, Katihar, Nagarcoil, Sri Ganganagar, Karawal Nagar, Mango, Thanjavur, Bulandshahr, Uluberia, Murwara, Sambhal, Singrauli, Nadiad, Secunderabad, Naihati, Yamunanagar, Bidhan Nagar, Pallavaram, Bidar, Munger, Panchkula, Burhanpur, Raurkela Industrial Township, Kharagpur, Dindigul, Gandhinagar, Hospet, Nangloi Jat, Malda, Ongole, Deoghar, Chapra, Haldia, Khandwa, Nandyal, Chittoor , Morena, Amroha, Anand, Bhind, Bhalswa Jahangir Pur, Madhyamgram, Bhiwani, Navi Mumbai Panvel Raigad, Baharampur, Ambala, Morvi, Fatehpur, Rae Bareli, Khora, Bhusawal, Orai, Bahraich, Vellore, Mahesana, Sambalpur, Raiganj, Sirsa, Danapur, Serampore, Sultan Pur Majra, Guna, Jaunpur, Panvel, Shivpuri, Surendranagar Dudhrej, Unnao, Hugli and Chinsurah, Alappuzha, Kottayam, Machilipatnam, Shimla, Adoni, Tenali, Proddatur, Saharsa, Hindupur, Sasaram, Hajipur, Bhimavaram, Dehri, Madanapalle, Siwan, Bettiah, Guntakal, Srikakulam, Motihari, Dharmavaram, Gudivada, Narasaraopet, Bagaha, Miryalaguda, Tadipatri, Kishanganj, Karaikudi, Suryapet, Jamalpur, Kavali, Tadepalligudem, Amaravati, Buxar, Jehanabad, Aurangabad.
